Identity
HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
ADTKD4,HNFJ2,RTD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5972
MIM: 179820
HGNC: 9958
Ensembl: ENSG00000143839
Variants:
dbSNP: 5972
ClinVar: 5972
TCGA: ENSG00000143839
COSMIC: REN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143839 | ENST00000272190 | P00797 |
| ENSG00000143839 | ENST00000638118 | A0A1B0GUZ2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA162356187 | muraglitazar | Chemical | ClinicalAnnotation | associated | PD | 18794727 | |
| PA443886 | Diabetes Mellitus | Disease | ClinicalAnnotation | associated | PD | 18794727 | |
| PA443994 | Edema | Disease | ClinicalAnnotation | associated | PD | 18794727 | |
| PA444528 | Hyperlipidemias | Disease | ClinicalAnnotation | associated | PD | 18794727 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38509149 | 2024 | Plasma renin as a novel prognostic biomarker of sepsis-associated acute respiratory distress syndrome. | 0 |
| 38622720 | 2024 | The role of the brain renin-angiotensin system in Parkinson´s disease. | 1 |
| 38509149 | 2024 | Plasma renin as a novel prognostic biomarker of sepsis-associated acute respiratory distress syndrome. | 0 |
| 38622720 | 2024 | The role of the brain renin-angiotensin system in Parkinson´s disease. | 1 |
| 36478297 | 2023 | The alternative renin-angiotensin-system (RAS) signalling pathway in prostate cancer and its link to the current COVID-19 pandemic. | 0 |
| 36481346 | 2023 | Counter-regulatory renin-angiotensin system in hypertension: Review and update in the era of COVID-19 pandemic. | 5 |
| 37569338 | 2023 | The Relationship between Renin-Angiotensin-Aldosterone System (RAAS) Activity, Osteoporosis and Estrogen Deficiency in Type 2 Diabetes. | 2 |
| 36478297 | 2023 | The alternative renin-angiotensin-system (RAS) signalling pathway in prostate cancer and its link to the current COVID-19 pandemic. | 0 |
| 36481346 | 2023 | Counter-regulatory renin-angiotensin system in hypertension: Review and update in the era of COVID-19 pandemic. | 5 |
| 37569338 | 2023 | The Relationship between Renin-Angiotensin-Aldosterone System (RAAS) Activity, Osteoporosis and Estrogen Deficiency in Type 2 Diabetes. | 2 |
| 33065209 | 2021 | The role of kallikrein-kinin and renin-angiotensin systems in COVID-19 infection. | 19 |
| 33173183 | 2021 | Sequence variants in the renin-angiotensin system genes are associated with isolated multicystic dysplastic kidney in children. | 1 |
| 33508746 | 2021 | Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions. | 11 |
| 33677630 | 2021 | Non-coding Single Nucleotide Variants of Renin and the (Pro)renin Receptor are Associated with Polygenic Diseases in a Bangladeshi Population. | 1 |
| 33750025 | 2021 | Confined placental mosaicism involving multiple de novo copy number variants associated with fetal growth restriction: A case report. | 2 |
Citation
Dessen P
REN (renin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45987/ren-(renin)
