AURKC (aurora kinase C)

2007-02-01  

Identity

HGNC
AURKC
LOCATION
19q13.43
LOCUSID
6795
ALIAS
AIE2,AIK3,ARK3,AurC,HEL-S-90,SPGF5,STK13,aurora-C
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6795
MIM: 603495
HGNC: 11391
Ensembl: ENSG00000105146

Variants:

dbSNP: 6795
ClinVar: 6795
TCGA: ENSG00000105146
COSMIC: AURKC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105146ENST00000302804Q9UQB9
ENSG00000105146ENST00000415300Q9UQB9
ENSG00000105146ENST00000448930A0A0A0MSY3
ENSG00000105146ENST00000594599M0QYK8
ENSG00000105146ENST00000596375B4DXA6
ENSG00000105146ENST00000598785Q9UQB9
ENSG00000105146ENST00000599062Q5Y191
ENSG00000105146ENST00000601799M0QX60

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
363264882023Computational study of the potential impact of AURKC missense SNPs on AURKC-INCENP interaction and their correlation to macrozoospermia.0
363264882023Computational study of the potential impact of AURKC missense SNPs on AURKC-INCENP interaction and their correlation to macrozoospermia.0
352184772022Aurora kinase genetic polymorphisms: an association study in Down syndrome and spontaneous abortion.1
352184772022Aurora kinase genetic polymorphisms: an association study in Down syndrome and spontaneous abortion.1
337252742021Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway.5
340306422021Co-relation with novel phosphorylation sites of IκBα and necroptosis in breast cancer cells.4
344611082021The oncogenic role of meiosis-specific Aurora kinase C in mitotic cells.4
344658132021Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme.1
337252742021Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway.5
340306422021Co-relation with novel phosphorylation sites of IκBα and necroptosis in breast cancer cells.4
344611082021The oncogenic role of meiosis-specific Aurora kinase C in mitotic cells.4
344658132021Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme.1
323999822020Mutational analysis of Aurora kinase C gene in Egyptian patients with macrozoospermia.2
324524022020Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction.4
331182052020Two frequent loss-of-function mutations in Aurora Kinase C gene in Algerian infertile men with macrozoospermia.0

Citation

Dessen P

AURKC (aurora kinase C)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46007/aurkc-(aurora-kinase-c)