Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5538
MIM: 600722
HGNC: 9325
Ensembl: ENSG00000131238
Variants:
dbSNP: 5538
ClinVar: 5538
TCGA: ENSG00000131238
COSMIC: PPT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37103469 | 2023 | Identification of PPT1 as a lysosomal core gene with prognostic value in hepatocellular carcinoma. | 1 |
| 37103469 | 2023 | Identification of PPT1 as a lysosomal core gene with prognostic value in hepatocellular carcinoma. | 1 |
| 36088080 | 2022 | Computational and structural investigation of Palmitoyl-Protein Thioesterase 1 (PPT1) protein causing Neuronal Ceroid Lipofuscinoses (NCL). | 2 |
| 36088080 | 2022 | Computational and structural investigation of Palmitoyl-Protein Thioesterase 1 (PPT1) protein causing Neuronal Ceroid Lipofuscinoses (NCL). | 2 |
| 33561134 | 2021 | Human INCL fibroblasts display abnormal mitochondrial and lysosomal networks and heightened susceptibility to ROS-induced cell death. | 0 |
| 33561134 | 2021 | Human INCL fibroblasts display abnormal mitochondrial and lysosomal networks and heightened susceptibility to ROS-induced cell death. | 0 |
| 30442709 | 2019 | PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. | 116 |
| 30442709 | 2019 | PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. | 116 |
| 29631617 | 2018 | Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. | 14 |
| 30541466 | 2018 | Batten disease: biochemical and molecular characterization revealing novel PPT1 and TPP1 gene mutations in Indian patients. | 6 |
| 29631617 | 2018 | Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. | 14 |
| 30541466 | 2018 | Batten disease: biochemical and molecular characterization revealing novel PPT1 and TPP1 gene mutations in Indian patients. | 6 |
| 28334871 | 2017 | Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease. | 9 |
| 28899863 | 2017 | A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles. | 108 |
| 28978646 | 2017 | Lactate-mediated mitoribosomal defects impair mitochondrial oxidative phosphorylation and promote hepatoma cell invasiveness. | 42 |
Citation
Dessen P
PPT1 (palmitoyl-protein thioesterase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46009/ppt1-(palmitoyl-protein-thioesterase-1)
