IL10RA (interleukin 10 receptor subunit alpha)

2007-02-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
CD210,CD210a,CDW210A,HIL-10R,IL-10R1,IL10R
FUSION GENES

Other Information

Locus ID:

NCBI: 3587
MIM: 146933
HGNC: 5964
Ensembl: ENSG00000110324

Variants:

dbSNP: 3587
ClinVar: 3587
TCGA: ENSG00000110324
COSMIC: IL10RA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110324ENST00000227752Q13651
ENSG00000110324ENST00000526544E9PKU2
ENSG00000110324ENST00000534574E9PPU4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
ToxoplasmosisKEGGko05145
ToxoplasmosisKEGGhsa05145
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-10 signalingREACTOMER-HSA-6783783

References

Pubmed IDYearTitleCitations
375110502023Association of IL10RA, IL10RB, and IL22RA Polymorphisms/Haplotypes with Susceptibility to and Clinical Manifestations of SLE.0
375110502023Association of IL10RA, IL10RB, and IL22RA Polymorphisms/Haplotypes with Susceptibility to and Clinical Manifestations of SLE.0
335951402021IL-10 receptor expression on lymphocytes and monocytes in children with food allergy.1
338494462021Characterization of novel and large fragment deletions in exon 1 of the IL10RA gene in Chinese children with very early onset inflammatory bowel diseases.4
348792212021Interleukin-10 receptor signaling promotes the maintenance of a PD-1(int) TCF-1(+) CD8(+) T cell population that sustains anti-tumor immunity.40
335951402021IL-10 receptor expression on lymphocytes and monocytes in children with food allergy.1
338494462021Characterization of novel and large fragment deletions in exon 1 of the IL10RA gene in Chinese children with very early onset inflammatory bowel diseases.4
348792212021Interleukin-10 receptor signaling promotes the maintenance of a PD-1(int) TCF-1(+) CD8(+) T cell population that sustains anti-tumor immunity.40
320340842020Erythema Nodosum Leprosum Neutrophil Subset Expressing IL-10R1 Transmigrates into Skin Lesions and Responds to IL-10.9
323061362020IL-10 suppresses IFN-γ-mediated signaling in lung adenocarcinoma.6
323805172020The effect of interleukin 10 polymorphisms on breast cancer susceptibility in Han women in Shaanxi Province.3
325874512020Intestinal dysbiosis in pediatric Crohn's disease patients with IL10RA mutations.12
326053392020[Relationship between gene polymorphism at rs2228055 locus in the exon region of interleukin-10 receptor A and susceptibility to food allergy in children].1
328389462020Identification of a novel signaling complex containing host chemokine receptor CXCR4, Interleukin-10 receptor, and human cytomegalovirus US27.3
320340842020Erythema Nodosum Leprosum Neutrophil Subset Expressing IL-10R1 Transmigrates into Skin Lesions and Responds to IL-10.9

Citation

Dessen P

IL10RA (interleukin 10 receptor subunit alpha)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46038/il10ra-(interleukin-10-receptor-subunit-alpha)