Identity
HGNC
LOCATION
17q22
LOCUSID
ALIAS
ARTS,BRADEION,C17orf47,CE5B3,H5,MART,PNUTL2,SEP4,SEPT4,hCDCREL-2,hucep-7
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5414
MIM: 603696
HGNC: 9165
Ensembl: ENSG00000108387
Variants:
dbSNP: 5414
ClinVar: 5414
TCGA: ENSG00000108387
COSMIC: SEPTIN4
RNA/Proteins
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Apoptosis | KEGG | ko04210 |
| Apoptosis | KEGG | hsa04210 |
| Apoptosis - multiple species | KEGG | ko04215 |
| Apoptosis - multiple species | KEGG | hsa04215 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36565718 | 2023 | The ARTS of p53-dependent mitochondrial apoptosis. | 9 |
| 36565718 | 2023 | The ARTS of p53-dependent mitochondrial apoptosis. | 9 |
| 36135717 | 2022 | Biallelic loss-of-function mutations in SEPTIN4 (C17ORF47), encoding a conserved annulus protein, cause thin midpiece spermatozoa and male infertility in humans. | 1 |
| 36135717 | 2022 | Biallelic loss-of-function mutations in SEPTIN4 (C17ORF47), encoding a conserved annulus protein, cause thin midpiece spermatozoa and male infertility in humans. | 1 |
| 33627621 | 2021 | p53 induces ARTS to promote mitochondrial apoptosis. | 15 |
| 33627621 | 2021 | p53 induces ARTS to promote mitochondrial apoptosis. | 15 |
| 31924572 | 2020 | Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury. | 29 |
| 32626973 | 2020 | Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts. | 3 |
| 31924572 | 2020 | Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury. | 29 |
| 32626973 | 2020 | Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts. | 3 |
| 28224479 | 2018 | Modulation of ARTS and XIAP by Parkin Is Associated with Carnosic Acid Protects SH-SY5Y Cells against 6-Hydroxydopamine-Induced Apoptosis. | 6 |
| 29366480 | 2018 | Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure. | 10 |
| 29991349 | 2018 | Untangling the Tauopathy for Alzheimer's disease and parkinsonism. | 22 |
| 28224479 | 2018 | Modulation of ARTS and XIAP by Parkin Is Associated with Carnosic Acid Protects SH-SY5Y Cells against 6-Hydroxydopamine-Induced Apoptosis. | 6 |
| 29366480 | 2018 | Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure. | 10 |
Citation
Dessen P
SEPTIN4 (septin 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46050/
