SUPT20H (SPT20 homolog, SAGA complex component)

2007-02-01  

Identity

HGNC
SUPT20H
LOCATION
13q13.3
LOCUSID
55578
ALIAS
C13,C13orf19,FAM48A,FP757,P38IP,SPT20
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55578
MIM: 613417
HGNC: 20596
Ensembl: ENSG00000102710

Variants:

dbSNP: 55578
ClinVar: 55578
TCGA: ENSG00000102710
COSMIC: SUPT20H

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102710ENST00000350612Q8NEM7
ENSG00000102710ENST00000356185Q8NEM7
ENSG00000102710ENST00000356185A0A024RDW2
ENSG00000102710ENST00000360252Q8NEM7
ENSG00000102710ENST00000360252A0A024RDW2
ENSG00000102710ENST00000464744Q8NEM7
ENSG00000102710ENST00000464744A0A024RDW2
ENSG00000102710ENST00000469488H7C5F9
ENSG00000102710ENST00000475892Q8NEM7
ENSG00000102710ENST00000490716R4GND2
ENSG00000102710ENST00000495071B4E2D5
ENSG00000102710ENST00000497318C9JQS2
ENSG00000102710ENST00000542180F6S7C4

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
312103712019FAM48A mediates compensatory autophagy induced by proteasome impairment.0
312103712019FAM48A mediates compensatory autophagy induced by proteasome impairment.0
275318772016p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma.16
275318772016p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma.16
242200282013The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.13
242200282013The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.13
198934882010Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP.128
198934882010Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP.128
191145502009The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.45
191145502009The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.45
166854012006Functional analyses of C13orf19/P38IP in prostate cell lines.1
166854012006Functional analyses of C13orf19/P38IP in prostate cell lines.1
159783282005Quantification of C13orf19/P38IP mRNA expression by quantitative real-time PCR in patients with urological malignancies.3
159783282005Quantification of C13orf19/P38IP mRNA expression by quantitative real-time PCR in patients with urological malignancies.3
120700152002Novel transcription factors in human CD34 antigen-positive hematopoietic cells.9

Citation

Dessen P

SUPT20H (SPT20 homolog, SAGA complex component)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46059/css/lib/teaching-explorer/humanGenome