CCKAR (cholecystokinin A receptor)

2007-02-01  

Identity

HGNC
CCKAR
LOCATION
4p15.2
LOCUSID
886
ALIAS
CCK-A,CCK1-R,CCK1R,CCKRA

Other Information

Locus ID:

NCBI: 886
MIM: 118444
HGNC: 1570
Ensembl: ENSG00000163394

Variants:

dbSNP: 886
ClinVar: 886
TCGA: ENSG00000163394
COSMIC: CCKAR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163394ENST00000295589P32238

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Neuroactive ligand-receptor interactionKEGGko04080
Calcium signaling pathwayKEGGhsa04020
Neuroactive ligand-receptor interactionKEGGhsa04080
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Insulin secretionKEGGhsa04911
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

References

Pubmed IDYearTitleCitations
340866702021Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.32
340866702021Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.32
330500502020Photodynamic Activation of Cholecystokinin 1 Receptor with Different Genetically Encoded Protein Photosensitizers and from Varied Subcellular Sites.3
330500502020Photodynamic Activation of Cholecystokinin 1 Receptor with Different Genetically Encoded Protein Photosensitizers and from Varied Subcellular Sites.3
265080212016Expression of cholecystokinin receptors in colon cancer and the clinical correlation in Taiwan.1
265519332016Functional dyspepsia is associated with GNβ3 C825T and CCK-AR T/C polymorphism.9
270722722016Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study.4
272875282016Polymorphism and Expression Profile of Cholecystokinin Type A Receptor in Relation to Gallstone Disease Susceptibility.0
265080212016Expression of cholecystokinin receptors in colon cancer and the clinical correlation in Taiwan.1
265519332016Functional dyspepsia is associated with GNβ3 C825T and CCK-AR T/C polymorphism.9
270722722016Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study.4
272875282016Polymorphism and Expression Profile of Cholecystokinin Type A Receptor in Relation to Gallstone Disease Susceptibility.0
258751762015Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.15
266087962015Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort.2
258751762015Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.15

Citation

Dessen P

CCKAR (cholecystokinin A receptor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46064/cancer-prone-explorer/js/hgnc