Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30009
MIM: 604895
HGNC: 11599
Ensembl: ENSG00000073861
Variants:
dbSNP: 30009
ClinVar: 30009
TCGA: ENSG00000073861
COSMIC: TBX21
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000073861 | ENST00000177694 | Q9UL17 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10832 | corticosteroids | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38101155 | 2024 | Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas. | 0 |
| 38468428 | 2024 | Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population. | 0 |
| 38101155 | 2024 | Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas. | 0 |
| 38468428 | 2024 | Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population. | 0 |
| 36796535 | 2023 | Association of TBX21 gene polymorphisms and acute anterior uveitis risk in a Chinese population: A case-control study. | 1 |
| 37039998 | 2023 | Expression analysis of IL-2, TBX21 and SOCS1 in peripheral blood cells of celiac disease patients reveals the diagnostic potential of IL-2. | 0 |
| 37067748 | 2023 | TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner. | 1 |
| 37279078 | 2023 | T-BET and EOMES sustain mature human NK cell identity and antitumor function. | 5 |
| 36796535 | 2023 | Association of TBX21 gene polymorphisms and acute anterior uveitis risk in a Chinese population: A case-control study. | 1 |
| 37039998 | 2023 | Expression analysis of IL-2, TBX21 and SOCS1 in peripheral blood cells of celiac disease patients reveals the diagnostic potential of IL-2. | 0 |
| 37067748 | 2023 | TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner. | 1 |
| 37279078 | 2023 | T-BET and EOMES sustain mature human NK cell identity and antitumor function. | 5 |
| 33040251 | 2021 | Role of the IL-23-T-bet/GATA3 Axis for the Pathogenesis of Ulcerative Colitis. | 4 |
| 33938192 | 2021 | Association of the rs17250932, rs4794067, and rs2240017 polymorphism in the TBX21 gene with autoimmune diseases: A meta-analysis. | 1 |
| 34160550 | 2021 | High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency. | 17 |
Citation
Dessen P
TBX21 (T-box transcription factor 21)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46077/tbx21-(t-box-transcription-factor-21)
