FN3K (fructosamine 3 kinase)

2007-02-01 Affiliation

Identity

HGNC

FN3K

LOCATION

17q25.3

LOCUSID

64122

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 64122
MIM: 608425
HGNC: 24822
Ensembl: ENSG00000167363

Variants:

dbSNP: 64122
ClinVar: 64122
TCGA: ENSG00000167363
COSMIC: FN3K

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000167363	ENST00000300784	Q9H479

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activation	REACTOME	R-HSA-163841

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
32636308	2020	A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily.	12
33208304	2020	FN3K expression in COPD: a potential comorbidity factor for cardiovascular disease.	2
32636308	2020	A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily.	12
33208304	2020	FN3K expression in COPD: a potential comorbidity factor for cardiovascular disease.	2
31398338	2019	The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.	69
31398338	2019	The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.	69
27461879	2016	The association between fructosamine-3 kinase 900C/G polymorphism, transferrin polymorphism and human herpesvirus-8 infection in diabetics living in South Kivu.	4
27461879	2016	The association between fructosamine-3 kinase 900C/G polymorphism, transferrin polymorphism and human herpesvirus-8 infection in diabetics living in South Kivu.	4
26352355	2015	Possible role of fructosamine 3-kinase genotyping for the management of diabetic patients.	8
26352355	2015	Possible role of fructosamine 3-kinase genotyping for the management of diabetic patients.	8
23492569	2014	Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality.	8
24908234	2014	Fructosamine 3-kinase and glyoxalase I polymorphisms and their association with soluble RAGE and adhesion molecules in diabetes.	8
23492569	2014	Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality.	8
24908234	2014	Fructosamine 3-kinase and glyoxalase I polymorphisms and their association with soluble RAGE and adhesion molecules in diabetes.	8
21253391	2011	Low red blood cell levels of deglycating enzymes in colorectal cancer patients.	3

Citation

Dessen P

FN3K (fructosamine 3 kinase)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46092/fn3k-(fructosamine-3-kinase)