DPEP1 (dipeptidase 1)

2007-02-01  

Identity

HGNC
LOCATION
16q24.3
LOCUSID
ALIAS
MBD1,MDP,RDP
FUSION GENES

Other Information

Locus ID:

NCBI: 1800
MIM: 179780
HGNC: 3002
Ensembl: ENSG00000015413

Variants:

dbSNP: 1800
ClinVar: 1800
TCGA: ENSG00000015413
COSMIC: DPEP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000015413ENST00000261615P16444
ENSG00000015413ENST00000261615A0A140VJI3
ENSG00000015413ENST00000393092P16444
ENSG00000015413ENST00000393092A0A140VJI3
ENSG00000015413ENST00000421184P16444
ENSG00000015413ENST00000421184A0A140VJI3
ENSG00000015413ENST00000568281H3BP43
ENSG00000015413ENST00000570029H3BQS5

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Arachidonic acid metabolismREACTOMER-HSA-2142753
Synthesis of Leukotrienes (LT) and Eoxins (EX)REACTOMER-HSA-2142691
Biological oxidationsREACTOMER-HSA-211859
Aflatoxin activation and detoxificationREACTOMER-HSA-5423646

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
223636582012DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma.78
200315782009Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.54
200315782009Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.54
208242892011DPEP1, expressed in the early stages of colon carcinogenesis, affects cancer cell invasiveness.12
151455222004Dipeptidase 1: a candidate tumor-specific molecular marker in colorectal carcinoma.11
121447772002Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis.10
268249872016Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer.7
210764632011Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1.6
263924082015Reintroduction of a Homocysteine Level-Associated Allele into East Asians by Neanderthal Introgression.2
238394952013Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer.0

Citation

Dessen P

DPEP1 (dipeptidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46097/dpep1-(dipeptidase-1)