Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54106
MIM: 605474
HGNC: 15633
Ensembl: ENSG00000239732
Variants:
dbSNP: 54106
ClinVar: 54106
TCGA: ENSG00000239732
COSMIC: TLR9
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000239732 | ENST00000360658 | Q9NR96 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 24776844, 28696418 | |
| PA443815 | Crohn Disease | Disease | ClinicalAnnotation | associated | PD | 24776844 | |
| PA445451 | Psoriasis | Disease | ClinicalAnnotation | associated | PD | 28696418 | |
| PA446116 | Inflammatory Bowel Diseases | Disease | ClinicalAnnotation | associated | PD | 24776844 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37585174 | 2024 | Synonymous mutations in TLR2 and TLR9 genes decrease COPD susceptibility in the Chinese Han population. | 1 |
| 37718198 | 2024 | Association between genetic variants of TLR2, TLR4, TLR9 and schizophrenia. | 0 |
| 38105756 | 2024 | TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma. | 0 |
| 38296538 | 2024 | Relationship of Toll-Like Receptor 7, 9, and 10 Polymorphisms and the Severity of Coronavirus Disease 2019. | 0 |
| 38354781 | 2024 | Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons. | 0 |
| 38537697 | 2024 | Epstein-Barr virus suppresses N(6)-methyladenosine modification of TLR9 to promote immune evasion. | 0 |
| 38746965 | 2024 | Tubular expression of Toll-like receptor 9 in lupus and primary membranous nephropathy. | 0 |
| 38918662 | 2024 | Investigation of TLR2 (-196 to -174del) and TLR9 (T-1486C) Gene Polymorphisms Association with Inflammatory Bowel Diseases. | 0 |
| 37585174 | 2024 | Synonymous mutations in TLR2 and TLR9 genes decrease COPD susceptibility in the Chinese Han population. | 1 |
| 37718198 | 2024 | Association between genetic variants of TLR2, TLR4, TLR9 and schizophrenia. | 0 |
| 38105756 | 2024 | TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma. | 0 |
| 38296538 | 2024 | Relationship of Toll-Like Receptor 7, 9, and 10 Polymorphisms and the Severity of Coronavirus Disease 2019. | 0 |
| 38354781 | 2024 | Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons. | 0 |
| 38537697 | 2024 | Epstein-Barr virus suppresses N(6)-methyladenosine modification of TLR9 to promote immune evasion. | 0 |
| 38746965 | 2024 | Tubular expression of Toll-like receptor 9 in lupus and primary membranous nephropathy. | 0 |
Citation
Dessen P
TLR9 (toll like receptor 9)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46112/tlr9
