Identity
HGNC
LOCATION
10p11.22
LOCUSID
ALIAS
AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6935
MIM: 189909
HGNC: 11642
Ensembl: ENSG00000148516
Variants:
dbSNP: 6935
ClinVar: 6935
TCGA: ENSG00000148516
COSMIC: ZEB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA62 | ATP1A1 | Gene | Pathway | associated | 23788015 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37318032 | 2024 | miR-200a-3p regulates epithelial-mesenchymal transition and inflammation in chronic rhinosinusitis with nasal polyps by targeting ZEB1 via ERK/p38 pathway. | 0 |
| 37812283 | 2024 | LINC01806 Promotes Breast Cancer Growth and Metastasis via Sponging miR-1286 to Disinhibit ZEB1 Expression. | 0 |
| 37857482 | 2024 | Loss-of-function variants in ZEB1 cause dominant anomalies of the corpus callosum with favourable cognitive prognosis. | 0 |
| 37989078 | 2024 | miR-186 regulates epithelial-mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1. | 0 |
| 38073440 | 2024 | lncRNA799/TBL1XR1/ZEB1 Axis Forms a Feedback Loop to Promote the Epithelial-Mesenchymal Transition of Cervical Cancer Cells. | 0 |
| 38183060 | 2024 | Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis. | 1 |
| 38363677 | 2024 | ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion. | 0 |
| 38366093 | 2024 | Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box-Binding Homeobox 1 Pathway. | 1 |
| 38449391 | 2024 | The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells. | 0 |
| 38468464 | 2024 | GINS1 promotes ZEB1-mediated epithelial-mesenchymal transition and tumor metastasis via β-catenin signaling in hepatocellular carcinoma. | 1 |
| 38519642 | 2024 | ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions. | 0 |
| 38702771 | 2024 | miR-200b-3p relieved inflammation in patients with heart failure by regulating ZEB1 expression. | 0 |
| 38752261 | 2024 | CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis. | 0 |
| 38760717 | 2024 | Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway. | 0 |
| 38954708 | 2024 | Endothelial cell specific molecule 1 promotes epithelial-mesenchymal transition of cervical cancer via the E-box binding homeobox 1. | 0 |
Citation
Dessen P
ZEB1 (zinc finger E-box binding homeobox 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46166/zeb1-(zinc-finger-e-box-binding-homeobox-1)
