Identity
HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
CANP,CANP1,CANPL1,SPG76,muCANP,muCL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 823
MIM: 114220
HGNC: 1476
Ensembl: ENSG00000014216
Variants:
dbSNP: 823
ClinVar: 823
TCGA: ENSG00000014216
COSMIC: CAPN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38151212 | 2024 | Remote ischemic preconditioning reduces mitochondrial apoptosis mediated by calpain 1 activation in myocardial ischemia-reperfusion injury through calcium channel subunit Cacna2d3. | 0 |
| 38878112 | 2024 | Otud6b induces pulmonary arterial hypertension by mediating the Calpain-1/HIF-1α signaling pathway. | 0 |
| 38151212 | 2024 | Remote ischemic preconditioning reduces mitochondrial apoptosis mediated by calpain 1 activation in myocardial ischemia-reperfusion injury through calcium channel subunit Cacna2d3. | 0 |
| 38878112 | 2024 | Otud6b induces pulmonary arterial hypertension by mediating the Calpain-1/HIF-1α signaling pathway. | 0 |
| 36924231 | 2023 | CAPN1 (Calpain1)-Dependent Cleavage of STIM1 (Stromal Interaction Molecule 1) Results in an Enhanced SOCE (Store-Operated Calcium Entry) in Human Neonatal Platelets. | 1 |
| 37468791 | 2023 | Spastic paraplegia type 76 due to novel CAPN1 mutations: three case reports with literature review. | 0 |
| 36924231 | 2023 | CAPN1 (Calpain1)-Dependent Cleavage of STIM1 (Stromal Interaction Molecule 1) Results in an Enhanced SOCE (Store-Operated Calcium Entry) in Human Neonatal Platelets. | 1 |
| 37468791 | 2023 | Spastic paraplegia type 76 due to novel CAPN1 mutations: three case reports with literature review. | 0 |
| 35149397 | 2022 | Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease. | 0 |
| 35756844 | 2022 | Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1. | 11 |
| 35149397 | 2022 | Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease. | 0 |
| 35756844 | 2022 | Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1. | 11 |
| 32352326 | 2021 | CAPN1 and hereditary spastic paraplegia: a novel variant in an Iranian family and overview of the genotype-phenotype correlation. | 4 |
| 32852077 | 2021 | The investigation of calpain in human placenta with fetal growth restriction. | 1 |
| 33486633 | 2021 | Increasing involvement of CAPN1 variants in spastic ataxias and phenotype-genotype correlations. | 4 |
Citation
Dessen P
CAPN1 (calpain 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46179/capn1-(calpain-1)
