AGTR2 (angiotensin II receptor type 2)

2007-02-01  

Identity

HGNC
LOCATION
Xq23
LOCUSID
ALIAS
AT2,ATGR2,MRX88

Other Information

Locus ID:

NCBI: 186
MIM: 300034
HGNC: 338
Ensembl: ENSG00000180772

Variants:

dbSNP: 186
ClinVar: 186
TCGA: ENSG00000180772
COSMIC: AGTR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180772ENST00000371906P50052

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Renin-angiotensin systemKEGGko04614
Neuroactive ligand-receptor interactionKEGGhsa04080
Renin-angiotensin systemKEGGhsa04614
Adrenergic signaling in cardiomyocytesKEGGhsa04261
Adrenergic signaling in cardiomyocytesKEGGko04261
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
151178352004Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries.47
146570202003A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy.45
288770312017Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.45
288770312017Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.45
198613492010The angiotensin II type 2 receptor in cardiovascular disease.39
283799442017Structural basis for selectivity and diversity in angiotensin II receptors.39
120894452002AGTR2 mutations in X-linked mental retardation.32
176303222007The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis.32
232553262013Angiotensin II type 2 receptor (AT2 R) localization and antagonist-mediated inhibition of capsaicin responses and neurite outgrowth in human and rat sensory neurons.31

Citation

Dessen P

AGTR2 (angiotensin II receptor type 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46183/agtr2-(angiotensin-ii-receptor-type-2)