IL17RC (interleukin 17 receptor C)

2007-02-01  

Identity

HGNC
IL17RC
LOCATION
3p25.3
LOCUSID
84818
ALIAS
CANDF9,IL17-RL,IL17RL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84818
MIM: 610925
HGNC: 18358
Ensembl: ENSG00000163702

Variants:

dbSNP: 84818
ClinVar: 84818
TCGA: ENSG00000163702
COSMIC: IL17RC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163702ENST00000295981Q8NAC3
ENSG00000163702ENST00000383812Q8NAC3
ENSG00000163702ENST00000403601Q8NAC3
ENSG00000163702ENST00000412901B4DI24
ENSG00000163702ENST00000413608Q8NAC3
ENSG00000163702ENST00000416074Q8NAC3
ENSG00000163702ENST00000424206F8WD65
ENSG00000163702ENST00000434756F8WE27
ENSG00000163702ENST00000436503C9K0M1
ENSG00000163702ENST00000438091C9JSZ3
ENSG00000163702ENST00000440502F8WEG5
ENSG00000163702ENST00000451165F6X4Z5
ENSG00000163702ENST00000451231F8WB43
ENSG00000163702ENST00000451271F8WC09
ENSG00000163702ENST00000455057Q8NAC3
ENSG00000163702ENST00000476810G3V177
ENSG00000163702ENST00000498214A8K3Q5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-17 signalingREACTOMER-HSA-448424
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 2
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
361256892023IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC.6
367010752023Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey.1
361256892023IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC.6
367010752023Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey.1
351674872021IL-17 Receptor C Signaling Controls CD4(+) T(H)17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases.11
351674872021IL-17 Receptor C Signaling Controls CD4(+) T(H)17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases.11
321875182020Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.36
321875182020Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.36
312919732019IL17RC affects the predisposition to thoracic ossification of the posterior longitudinal ligament.4
314815252019Interleukin-17 receptor C gene polymorphism reduces treatment effect and promotes poor prognosis of ischemic stroke.6
312919732019IL17RC affects the predisposition to thoracic ossification of the posterior longitudinal ligament.4
314815252019Interleukin-17 receptor C gene polymorphism reduces treatment effect and promotes poor prognosis of ischemic stroke.6
295847882018IL-17A, IL-17RC polymorphisms and IL17 plasma levels in Tunisian patients with rheumatoid arthritis.16
296956542018Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.3
297644672018Association of IL17RC and COL6A1 genetic polymorphisms with susceptibility to ossification of the thoracic posterior longitudinal ligament in Chinese patients.10

Citation

Dessen P

IL17RC (interleukin 17 receptor C)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46195/il17rc-(interleukin-17-receptor-c)