Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
PREP1,pkonx1c
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5316
MIM: 602100
HGNC: 9022
Ensembl: ENSG00000160199
Variants:
dbSNP: 5316
ClinVar: 5316
TCGA: ENSG00000160199
COSMIC: PKNOX1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160199 | ENST00000291547 | P55347 |
| ENSG00000160199 | ENST00000291547 | Q96I87 |
| ENSG00000160199 | ENST00000432907 | E7EPN6 |
| ENSG00000160199 | ENST00000560448 | H0YM69 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36356379 | 2023 | Polyunsaturated fatty acids ameliorate renal stone-induced renal tubular damage via miR-93-5p/Pknox1 axis. | 2 |
| 37864517 | 2023 | PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway. | 0 |
| 36356379 | 2023 | Polyunsaturated fatty acids ameliorate renal stone-induced renal tubular damage via miR-93-5p/Pknox1 axis. | 2 |
| 37864517 | 2023 | PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway. | 0 |
| 33033354 | 2020 | Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. | 5 |
| 33033354 | 2020 | Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. | 5 |
| 29453404 | 2018 | PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry. | 8 |
| 30338914 | 2018 | MiR-17 family-mediated regulation of Pknox1 influences hepatic steatosis and insulin signaling. | 10 |
| 29453404 | 2018 | PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry. | 8 |
| 30338914 | 2018 | MiR-17 family-mediated regulation of Pknox1 influences hepatic steatosis and insulin signaling. | 10 |
| 25157139 | 2014 | Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma. | 52 |
| 25157139 | 2014 | Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma. | 52 |
| 22347417 | 2012 | Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia. | 8 |
| 22347417 | 2012 | Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia. | 8 |
| 21715654 | 2011 | Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability. | 20 |
Citation
Dessen P
PKNOX1 (PBX/knotted 1 homeobox 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46241/pknox1-(pbx-knotted-1-homeobox-1)
