ZNF148 (zinc finger protein 148)

2007-02-01  

Identity

HGNC
ZNF148
LOCATION
3q21.2
LOCUSID
7707
ALIAS
BERF-1,BFCOL1,GDACCF,HT-BETA,ZBP-89,ZFP148,pHZ-52
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7707
MIM: 601897
HGNC: 12933
Ensembl: ENSG00000163848

Variants:

dbSNP: 7707
ClinVar: 7707
TCGA: ENSG00000163848
COSMIC: ZNF148

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163848ENST00000360647Q9UQR1
ENSG00000163848ENST00000465763C9J6Y6
ENSG00000163848ENST00000468369G5E9X2
ENSG00000163848ENST00000471196C9JRX0
ENSG00000163848ENST00000484491Q9UQR1
ENSG00000163848ENST00000485866Q9UQR1
ENSG00000163848ENST00000492394Q9UQR1
ENSG00000163848ENST00000495019C9K0U4

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375801132024Further delineation of the rare GDACCF (global developmental delay, absent or hypoplastic corpus callosum, dysmorphic facies syndrome): genotype and phenotype of 22 patients with ZNF148 mutations.0
382972802024ZNF148 inhibits HBV replication by downregulating RXRα transcription.1
375801132024Further delineation of the rare GDACCF (global developmental delay, absent or hypoplastic corpus callosum, dysmorphic facies syndrome): genotype and phenotype of 22 patients with ZNF148 mutations.0
382972802024ZNF148 inhibits HBV replication by downregulating RXRα transcription.1
367106622023Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis.4
370630772023Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.6
372886642023Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.1
367106622023Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis.4
370630772023Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.6
372886642023Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.1
338643832021Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.8
338643832021Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.8
318742462020ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.13
320609662020Upregulation of ZNF148 in SDHB-deficient gastrointestinal stromal tumor potentiates Forkhead box M1-mediated transcription and promotes tumor cell invasion.3
318742462020ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.13

Citation

Dessen P

ZNF148 (zinc finger protein 148)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46260/js/css/humanGenome