Identity
HGNC
LOCATION
11q24.3
LOCUSID
ALIAS
CIR,GIRK4,KATP1,KIR3.4,LQT13
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3762
MIM: 600734
HGNC: 6266
Ensembl: ENSG00000120457
Variants:
dbSNP: 3762
ClinVar: 3762
TCGA: ENSG00000120457
COSMIC: KCNJ5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120457 | ENST00000338350 | P48544 |
| ENSG00000120457 | ENST00000529694 | P48544 |
| ENSG00000120457 | ENST00000533599 | P48544 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36950676 | 2023 | Cardiovascular and metabolic characters of KCNJ5 somatic mutations in primary aldosteronism. | 3 |
| 37463983 | 2023 | KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma. | 0 |
| 37894977 | 2023 | The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes. | 2 |
| 36950676 | 2023 | Cardiovascular and metabolic characters of KCNJ5 somatic mutations in primary aldosteronism. | 3 |
| 37463983 | 2023 | KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma. | 0 |
| 37894977 | 2023 | The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes. | 2 |
| 34957562 | 2022 | A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5). | 3 |
| 35311227 | 2022 | KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. | 1 |
| 35779252 | 2022 | Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults. | 3 |
| 36012306 | 2022 | Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma. | 4 |
| 34957562 | 2022 | A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5). | 3 |
| 35311227 | 2022 | KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma. | 1 |
| 35779252 | 2022 | Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults. | 3 |
| 36012306 | 2022 | Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma. | 4 |
| 33199157 | 2021 | Familial periodic paralysis associated with a rare KCNJ5 variant that supposed to have incomplete penetrance. | 1 |
Citation
Dessen P
KCNJ5 (potassium inwardly rectifying channel subfamily J member 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46270/kcnj5-(potassium-inwardly-rectifying-channel-subfamily-j-member-5)
