SIRT7 (sirtuin 7)

2007-02-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
SIR2L7
FUSION GENES

Other Information

Locus ID:

NCBI: 51547
MIM: 606212
HGNC: 14935
Ensembl: ENSG00000187531

Variants:

dbSNP: 51547
ClinVar: 51547
TCGA: ENSG00000187531
COSMIC: SIRT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187531ENST00000328666Q9NRC8
ENSG00000187531ENST00000572902I3L480
ENSG00000187531ENST00000575360I3L2A4

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376762632024SIRT7: the seventh key to unlocking the mystery of aging.6
381983572024Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation.1
383605982024SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.0
384112742024KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.0
384525832024SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.0
387971532024SIRT7 promotes mitochondrial biogenesis to render the adaptive resistance to MAPK inhibition in melanoma.0
388700552024SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.2
376762632024SIRT7: the seventh key to unlocking the mystery of aging.6
381983572024Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation.1
383605982024SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.0
384112742024KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.0
384525832024SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.0
387971532024SIRT7 promotes mitochondrial biogenesis to render the adaptive resistance to MAPK inhibition in melanoma.0
388700552024SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.2
359413022023SIRT7 silencing by miR-152-3p confers cell apoptosis and renal functional impairment induced by renal ischaemia/reperfusion injury.2

Citation

Dessen P

SIRT7 (sirtuin 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46278/sirt7-(sirtuin-7)