Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2020
MIM: 131310
HGNC: 3343
Ensembl: ENSG00000164778
Variants:
dbSNP: 2020
ClinVar: 2020
TCGA: ENSG00000164778
COSMIC: EN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164778 | ENST00000297375 | P19622 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37987507 | 2024 | Engrailed 2 serves as a master regulator of the super-enhancer in the TNC gene locus in non-small cell lung cancer. | 0 |
| 37987507 | 2024 | Engrailed 2 serves as a master regulator of the super-enhancer in the TNC gene locus in non-small cell lung cancer. | 0 |
| 35169223 | 2022 | Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer. | 9 |
| 35169223 | 2022 | Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer. | 9 |
| 33685351 | 2021 | Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis. | 17 |
| 33685351 | 2021 | Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis. | 17 |
| 31692391 | 2020 | Is Engrailed-2 (EN2) a truly promising biomarker in prostate cancer detection? | 0 |
| 32434869 | 2020 | Bidirectional transfer of homeoprotein EN2 across the plasma membrane requires PIP(2). | 17 |
| 32539763 | 2020 | Altered staining patterns and expression level of Engrailed-2 in benign prostatic hyperplasia and prostate Cancer predict prostatic disease progression. | 1 |
| 32732864 | 2020 | EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer. | 19 |
| 31692391 | 2020 | Is Engrailed-2 (EN2) a truly promising biomarker in prostate cancer detection? | 0 |
| 32434869 | 2020 | Bidirectional transfer of homeoprotein EN2 across the plasma membrane requires PIP(2). | 17 |
| 32539763 | 2020 | Altered staining patterns and expression level of Engrailed-2 in benign prostatic hyperplasia and prostate Cancer predict prostatic disease progression. | 1 |
| 32732864 | 2020 | EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer. | 19 |
| 30914795 | 2019 | Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma. | 8 |
Citation
Dessen P
EN2 (engrailed homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46279/en2-(engrailed-homeobox-2)
