SALL2 (spalt like transcription factor 2)

2007-02-01  

Identity

HGNC
SALL2
LOCATION
14q11.2
LOCUSID
6297
ALIAS
COLB,HSAL2,Sal-2,ZNF795,p150(Sal2)
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6297
MIM: 602219
HGNC: 10526
Ensembl: ENSG00000165821

Variants:

dbSNP: 6297
ClinVar: 6297
TCGA: ENSG00000165821
COSMIC: SALL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165821ENST00000450879E7EW59
ENSG00000165821ENST00000537235F5H433
ENSG00000165821ENST00000541965F5H1G6
ENSG00000165821ENST00000546363H0YFS7
ENSG00000165821ENST00000611430A0A087X1T9
ENSG00000165821ENST00000613414A0A0B4J2F7
ENSG00000165821ENST00000614342Q9Y467

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
311880172019SALL2 Is a Novel Prognostic Methylation Marker in Patients with Oral Squamous Carcinomas: Associations with SALL1 and SALL3 Methylation Status.6
311880172019SALL2 Is a Novel Prognostic Methylation Marker in Patients with Oral Squamous Carcinomas: Associations with SALL1 and SALL3 Methylation Status.6
297831892018Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells.2
297831892018Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells.2
284308742017Developmental SALL2 transcription factor: a new player in cancer.21
292289222017Effect of siRNA-silencing of SALL2 gene on growth, migration and invasion of human ovarian carcinoma A2780 cells.6
284308742017Developmental SALL2 transcription factor: a new player in cancer.21
292289222017Effect of siRNA-silencing of SALL2 gene on growth, migration and invasion of human ovarian carcinoma A2780 cells.6
255809512015Sal-like protein 2 upregulates p16 expression through a proximal promoter element.12
256088372015The tumor suppressor protein p150(Sal2) in carcinogenesis.4
255809512015Sal-like protein 2 upregulates p16 expression through a proximal promoter element.12
256088372015The tumor suppressor protein p150(Sal2) in carcinogenesis.4
244129332014Mutation of SALL2 causes recessive ocular coloboma in humans and mice.22
244129332014Mutation of SALL2 causes recessive ocular coloboma in humans and mice.22
232735472013Promoter methylation of the SALL2 tumor suppressor gene in ovarian cancers.19

Citation

Dessen P

SALL2 (spalt like transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46308/sall2-(spalt-like-transcription-factor-2)