Identity
HGNC
LOCATION
Xp21.1
LOCUSID
ALIAS
AMCBX2,CGD,CGDX,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1536
MIM: 300481
HGNC: 2578
Ensembl: ENSG00000165168
Variants:
dbSNP: 1536
ClinVar: 1536
TCGA: ENSG00000165168
COSMIC: CYBB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165168 | ENST00000378588 | P04839 |
| ENSG00000165168 | ENST00000378588 | A0A0S2Z3S6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37347818 | 2024 | Association Between Serum Levels of Nicotinamide-Adenine Dinucleotide Phosphate Oxidase 2 and the Development of Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting: A Prospective Pilot Study. | 0 |
| 37925067 | 2024 | CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages. | 0 |
| 38355798 | 2024 | Structure of human phagocyte NADPH oxidase in the activated state. | 4 |
| 38460811 | 2024 | Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway. | 1 |
| 38805284 | 2024 | Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2. | 0 |
| 37347818 | 2024 | Association Between Serum Levels of Nicotinamide-Adenine Dinucleotide Phosphate Oxidase 2 and the Development of Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting: A Prospective Pilot Study. | 0 |
| 37925067 | 2024 | CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages. | 0 |
| 38355798 | 2024 | Structure of human phagocyte NADPH oxidase in the activated state. | 4 |
| 38460811 | 2024 | Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway. | 1 |
| 38805284 | 2024 | Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2. | 0 |
| 35997928 | 2023 | De Novo Somatic Mosaicism of CYBB Caused by Intronic LINE-1 Element Insertion Resulting in Chronic Granulomatous Disease. | 2 |
| 36332749 | 2023 | NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients. | 6 |
| 37175412 | 2023 | NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation. | 6 |
| 37247898 | 2023 | The Expression and Role of NADPH Oxidase 2 in Colon Cancer. | 0 |
| 37277492 | 2023 | Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10. | 3 |
Citation
Dessen P
CYBB (cytochrome b-245 beta chain)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46322/cybb-(cytochrome-b-245-beta-chain)
