C1D (C1D nuclear receptor corepressor)

2007-02-01  

Identity

HGNC
LOCATION
2p14
LOCUSID
ALIAS
LRP1,Rrp47,SUN-CoR,SUNCOR,hC1D
FUSION GENES

Other Information

Locus ID:

NCBI: 10438
MIM: 606997
HGNC: 29911
Ensembl: ENSG00000197223

Variants:

dbSNP: 10438
ClinVar: 10438
TCGA: ENSG00000197223
COSMIC: C1D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197223ENST00000355848Q13901
ENSG00000197223ENST00000407324J3KPZ4
ENSG00000197223ENST00000409302Q13901
ENSG00000197223ENST00000410067Q13901

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
174127072007C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.62
96790631998DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D.20
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
118017382002DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).15
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
175997752007C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome.5
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5
205305792010XPB induces C1D expression to counteract UV-induced apoptosis.3
301656702018C1D is not directly involved in the repair of UV-damaged DNA but protects cells from oxidative stress by regulating gene expressions in human cell lines.0

Citation

Dessen P

C1D (C1D nuclear receptor corepressor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46324/c1d-(c1d-nuclear-receptor-corepressor)