Identity
HGNC
LOCATION
11p15.1
LOCUSID
ALIAS
HEL-S-109,NEFA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4925
MIM: 608020
HGNC: 8044
Ensembl: ENSG00000070081
Variants:
dbSNP: 4925
ClinVar: 4925
TCGA: ENSG00000070081
COSMIC: NUCB2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | ClinicalAnnotation, Literature, MultilinkAnnotation | associated | PD | 24560520, 31327267 | |
| PA449899 | hydrochlorothiazide | Chemical | ClinicalAnnotation | associated | PD | 31327267 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36594093 | 2023 | Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy. | 4 |
| 36678225 | 2023 | Does NUCB2/Nesfatin-1 Influence Eating Behaviors in Obese Patients with Binge Eating Disorder? Toward a Neurobiological Pathway. | 5 |
| 36859270 | 2023 | Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway. | 0 |
| 37169340 | 2023 | Nucleobindin-2 Mediates Transforming Growth Factor-β1-Driven Phenotypes in Zinc Finger E-Box Binding Homeobox 1-High Uterine Carcinosarcoma. | 2 |
| 37277807 | 2023 | NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway. | 1 |
| 37385089 | 2023 | NUCB2/nesfatin-1 in the acute stress response of obese women with high and low anxiety. | 0 |
| 37714885 | 2023 | High plasma nesfatin-1 level in Chinese adolescents with depression. | 2 |
| 37830634 | 2023 | Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma. | 1 |
| 36594093 | 2023 | Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy. | 4 |
| 36678225 | 2023 | Does NUCB2/Nesfatin-1 Influence Eating Behaviors in Obese Patients with Binge Eating Disorder? Toward a Neurobiological Pathway. | 5 |
| 36859270 | 2023 | Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway. | 0 |
| 37169340 | 2023 | Nucleobindin-2 Mediates Transforming Growth Factor-β1-Driven Phenotypes in Zinc Finger E-Box Binding Homeobox 1-High Uterine Carcinosarcoma. | 2 |
| 37277807 | 2023 | NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway. | 1 |
| 37385089 | 2023 | NUCB2/nesfatin-1 in the acute stress response of obese women with high and low anxiety. | 0 |
| 37714885 | 2023 | High plasma nesfatin-1 level in Chinese adolescents with depression. | 2 |
Citation
Dessen P
NUCB2 (nucleobindin 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46341/nucb2-(nucleobindin-2)
