CALD1 (caldesmon 1)

2007-02-01  

Identity

HGNC
LOCATION
7q33
LOCUSID
ALIAS
CDM,H-CAD,HCAD,L-CAD,LCAD,NAG22
FUSION GENES

Other Information

Locus ID:

NCBI: 800
MIM: 114213
HGNC: 1441
Ensembl: ENSG00000122786

Variants:

dbSNP: 800
ClinVar: 800
TCGA: ENSG00000122786
COSMIC: CALD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122786ENST00000361675Q05682
ENSG00000122786ENST00000361901Q05682
ENSG00000122786ENST00000361901A0A140VKA0
ENSG00000122786ENST00000393118Q05682
ENSG00000122786ENST00000417172Q05682
ENSG00000122786ENST00000417172A0A140VKA0
ENSG00000122786ENST00000422748Q05682
ENSG00000122786ENST00000424922Q05682
ENSG00000122786ENST00000430085F8WE61
ENSG00000122786ENST00000435928C9JE79
ENSG00000122786ENST00000436461C9J813
ENSG00000122786ENST00000443197E9PGZ1
ENSG00000122786ENST00000445569C9JEK3
ENSG00000122786ENST00000454108C9JE79
ENSG00000122786ENST00000495522E7EX44

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
183537642008Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis.101
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
176312932007Caldesmon suppresses cancer cell invasion by regulating podosome/invadopodium formation.30
198346102009Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling.22
154567522004Modes of caldesmon binding to actin: sites of caldesmon contact and modulation of interactions by phosphorylation.18
187721422008Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.18
152263742004Caldesmon mutant defective in Ca(2+)-calmodulin binding interferes with assembly of stress fibers and affects cell morphology, growth and motility.17
151616542004Differential expression of splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization versus normal brain microvasculature.15
232656412013Identification and functional validation of caldesmon as a potential gastric cancer metastasis-associated protein.15
234183482013cGMP-dependent protein kinase Iβ regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon.15

Citation

Dessen P

CALD1 (caldesmon 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46343/cald1-(caldesmon-1)