Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8751
MIM: 605548
HGNC: 193
Ensembl: ENSG00000143537
Variants:
dbSNP: 8751
ClinVar: 8751
TCGA: ENSG00000143537
COSMIC: ADAM15
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| Degradation of the extracellular matrix | REACTOME | R-HSA-1474228 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36330793 | 2023 | Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway. | 2 |
| 37602921 | 2023 | Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors. | 0 |
| 36330793 | 2023 | Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway. | 2 |
| 37602921 | 2023 | Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors. | 0 |
| 33208450 | 2021 | ADAM15 Participates in Tick-Borne Encephalitis Virus Replication. | 4 |
| 34426560 | 2021 | ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma. | 7 |
| 34685689 | 2021 | A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts. | 1 |
| 33208450 | 2021 | ADAM15 Participates in Tick-Borne Encephalitis Virus Replication. | 4 |
| 34426560 | 2021 | ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma. | 7 |
| 34685689 | 2021 | A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts. | 1 |
| 32522006 | 2020 | ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. | 17 |
| 32677970 | 2020 | ADAM15 expression is increased in lung CD8(+) T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction. | 8 |
| 32522006 | 2020 | ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. | 17 |
| 32677970 | 2020 | ADAM15 expression is increased in lung CD8(+) T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction. | 8 |
| 30003689 | 2019 | ADAM15 in Apoptosis Resistance of Synovial Fibroblasts: Converting Fas/CD95 Death Signals Into the Activation of Prosurvival Pathways by Calmodulin Recruitment. | 5 |
Citation
Dessen P
ADAM15 (ADAM metallopeptidase domain 15)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46345/adam15-(adam-metallopeptidase-domain-15)
