Identity
HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
BFT,CCF,LBNBG,POTX,PTX1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5307
MIM: 602149
HGNC: 9004
Ensembl: ENSG00000069011
Variants:
dbSNP: 5307
ClinVar: 5307
TCGA: ENSG00000069011
COSMIC: PITX1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36334221 | 2023 | PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization. | 2 |
| 36334221 | 2023 | PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization. | 2 |
| 36360195 | 2022 | What Is the Exact Contribution of PITX1 and TBX4 Genes in Clubfoot Development? An Italian Study. | 2 |
| 36360195 | 2022 | What Is the Exact Contribution of PITX1 and TBX4 Genes in Clubfoot Development? An Italian Study. | 2 |
| 33763840 | 2021 | CircPITX1 Regulates Proliferation, Angiogenesis, Migration, Invasion, and Cell Cycle of Human Glioblastoma Cells by Targeting miR-584-5p/KPNB1 Axis. | 8 |
| 34215221 | 2021 | Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer. | 3 |
| 34526609 | 2021 | PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes. | 5 |
| 34868397 | 2021 | Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification. | 1 |
| 33763840 | 2021 | CircPITX1 Regulates Proliferation, Angiogenesis, Migration, Invasion, and Cell Cycle of Human Glioblastoma Cells by Targeting miR-584-5p/KPNB1 Axis. | 8 |
| 34215221 | 2021 | Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer. | 3 |
| 34526609 | 2021 | PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes. | 5 |
| 34868397 | 2021 | Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification. | 1 |
| 32518174 | 2020 | Rare and de novo duplications containing SHOX in clubfoot. | 6 |
| 32598510 | 2020 | Mandibular-pelvic-patellar syndrome is a novel PITX1-related disorder due to alteration of PITX1 transactivation ability. | 1 |
| 32759168 | 2020 | The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene. | 8 |
Citation
Dessen P
PITX1 (paired like homeodomain 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46355/pitx1-(paired-like-homeodomain-1)
