Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 445
MIM: 603470
HGNC: 758
Ensembl: ENSG00000130707
Variants:
dbSNP: 445
ClinVar: 445
TCGA: ENSG00000130707
COSMIC: ASS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166114316 | sodium phenylbutyrate | Chemical | LabelAnnotation | associated | |||
| PA166176020 | sodium benzoate / sodium phenylacetate | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36562411 | 2023 | Serum extracellular vesicle-derived ASS1 is a promising predictor for the occurrence of HEV-ALF. | 3 |
| 36669126 | 2023 | BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification. | 4 |
| 36680390 | 2023 | Analysis of ASS1 gene in ten unrelated middle eastern families with citrullinemia type 1 identifies rare and novel variants. | 2 |
| 36995581 | 2023 | Downregulation of argininosuccinate synthase 1 (ASS1) is associated with hypoxia in placental development. | 2 |
| 37254538 | 2023 | Polymorphic Variants of ASS1 Gene Related to Arginine Metabolism and the Risk of HCC. | 1 |
| 37906139 | 2023 | [Clinical and ASS1 gene variant analysis of three Chinese pedigrees affected with Citrullinemia type I]. | 0 |
| 36562411 | 2023 | Serum extracellular vesicle-derived ASS1 is a promising predictor for the occurrence of HEV-ALF. | 3 |
| 36669126 | 2023 | BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification. | 4 |
| 36680390 | 2023 | Analysis of ASS1 gene in ten unrelated middle eastern families with citrullinemia type 1 identifies rare and novel variants. | 2 |
| 36995581 | 2023 | Downregulation of argininosuccinate synthase 1 (ASS1) is associated with hypoxia in placental development. | 2 |
| 37254538 | 2023 | Polymorphic Variants of ASS1 Gene Related to Arginine Metabolism and the Risk of HCC. | 1 |
| 37906139 | 2023 | [Clinical and ASS1 gene variant analysis of three Chinese pedigrees affected with Citrullinemia type I]. | 0 |
| 35674458 | 2022 | PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway. | 5 |
| 35674458 | 2022 | PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway. | 5 |
| 33508432 | 2021 | Therapeutic targeting of argininosuccinate synthase 1 (ASS1)-deficient pulmonary fibrosis. | 11 |
Citation
Dessen P
ASS1 (argininosuccinate synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46363/ass1-(argininosuccinate-synthase-1)
