Identity
HGNC
LOCATION
Xq22.3
LOCUSID
ALIAS
ARTS,CMTX5,DFN2,DFNX1,PPRibP,PRS-I,PRSI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5631
MIM: 311850
HGNC: 9462
Ensembl: ENSG00000147224
Variants:
dbSNP: 5631
ClinVar: 5631
TCGA: ENSG00000147224
COSMIC: PRPS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35039981 | 2022 | Circular RNA circKIF2A Contributes to the Progression of Neuroblastoma Through Regulating PRPS1 Expression by Sponging miR-377-3p. | 4 |
| 35039981 | 2022 | Circular RNA circKIF2A Contributes to the Progression of Neuroblastoma Through Regulating PRPS1 Expression by Sponging miR-377-3p. | 4 |
| 33493137 | 2021 | PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness. | 2 |
| 34636169 | 2021 | NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells. | 3 |
| 33493137 | 2021 | PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness. | 2 |
| 34636169 | 2021 | NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells. | 3 |
| 31773495 | 2020 | A novel mutation in gene of PRPS1 in a young Chinese woman with X-linked gout: a case report and review of the literature. | 5 |
| 32391636 | 2020 | Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma. | 5 |
| 32781272 | 2020 | PRPS1 loss-of-function variants, from isolated hearing loss to severe congenital encephalopathy: New cases and literature review. | 7 |
| 33105440 | 2020 | SNHG16 knockdown inhibits tumorigenicity of neuroblastoma in children via miR-15b-5p/PRPS1 axis. | 4 |
| 31773495 | 2020 | A novel mutation in gene of PRPS1 in a young Chinese woman with X-linked gout: a case report and review of the literature. | 5 |
| 32391636 | 2020 | Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma. | 5 |
| 32781272 | 2020 | PRPS1 loss-of-function variants, from isolated hearing loss to severe congenital encephalopathy: New cases and literature review. | 7 |
| 33105440 | 2020 | SNHG16 knockdown inhibits tumorigenicity of neuroblastoma in children via miR-15b-5p/PRPS1 axis. | 4 |
| 31253668 | 2019 | Cell-Cycle-Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis. | 20 |
Citation
Dessen P
PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46404/prps1
