CDR2 (cerebellar degeneration related protein 2)

2007-02-01  

Identity

HGNC
LOCATION
16p12.2
LOCUSID
ALIAS
CDR62,Yo
FUSION GENES

Other Information

Locus ID:

NCBI: 1039
MIM: 117340
HGNC: 1799
Ensembl: ENSG00000140743

Variants:

dbSNP: 1039
ClinVar: 1039
TCGA: ENSG00000140743
COSMIC: CDR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140743ENST00000268383Q01850
ENSG00000140743ENST00000561630H3BQS4
ENSG00000140743ENST00000563573H3BN65
ENSG00000140743ENST00000564542H3BU23
ENSG00000140743ENST00000567010H3BUE0
ENSG00000140743ENST00000567406H3BTR1

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
98095591998Tumor-specific killer cells in paraneoplastic cerebellar degeneration.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
104657861999The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival.35
210801652011CDR2 antigen and Yo antibodies.13
292996672018Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration.10
150812532004An interferon-gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies.7
223517482012Human epidermal growth factor receptor 2 overexpression in breast cancer of patients with anti-Yo--associated paraneoplastic cerebellar degeneration.7
195819252009Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response.5
287105112017Cerebellar degeneration-related proteins 2 and 2-like are present in ovarian cancer in patients with and without Yo antibodies.5
160547802005Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21).3

Citation

Dessen P

CDR2 (cerebellar degeneration related protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46428/cdr2-(cerebellar-degeneration-related-protein-2)