CD83 (CD83 molecule)

Identity

HGNC

CD83

LOCATION

6p23

LOCUSID

9308

ALIAS

BL11,HB15

FUSION GENES

Show Gene Fusions

Other Information

Locus ID:

NCBI: 9308
MIM: 604534
HGNC: 1703
Ensembl: ENSG00000112149

Variants:

dbSNP: 9308
ClinVar: 9308
TCGA: ENSG00000112149
COSMIC: CD83

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000112149	ENST00000379153	Q01151
ENSG00000112149	ENST00000612003	A0A087WX61

Expression (GTEx)

0

10

20

30

40

50

60

70

80

90

100

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
32529460	2020	Soluble CD83 suppresses experimental food allergy via regulating aberrant T helper 2 responses.	0
32529460	2020	Soluble CD83 suppresses experimental food allergy via regulating aberrant T helper 2 responses.	0
32572123	2020	Difference in Presence and Number of CD83(+) Dendritic Cells in Patients with Ulcerative Colitis and Crohn's Disease.	6
33455090	2021	Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses.	8
33455090	2021	Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses.	8
34831294	2021	Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing's Sarcoma, Enhancing T Cell Cytotoxicity.	3
34831294	2021	Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing's Sarcoma, Enhancing T Cell Cytotoxicity.	3
36003376	2022	The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis.	5
36003376	2022	The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis.	5
36622700	2023	Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality.	5

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Citation

Dessen P

CD83 (CD83 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46441