ADIPOR2 (adiponectin receptor 2)

2007-02-01  

Identity

HGNC
LOCATION
12p13.33
LOCUSID
ALIAS
ACDCR2,PAQR2
FUSION GENES

Other Information

Locus ID:

NCBI: 79602
MIM: 607946
HGNC: 24041
Ensembl: ENSG00000006831

Variants:

dbSNP: 79602
ClinVar: 79602
TCGA: ENSG00000006831
COSMIC: ADIPOR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006831ENST00000357103Q86V24

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Adipocytokine signaling pathwayKEGGko04920
Adipocytokine signaling pathwayKEGGhsa04920
Non-alcoholic fatty liver disease (NAFLD)KEGGhsa04932
Non-alcoholic fatty liver disease (NAFLD)KEGGko04932
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
MetabolismREACTOMER-HSA-1430728
Integration of energy metabolismREACTOMER-HSA-163685
AMPK inhibits chREBP transcriptional activation activityREACTOMER-HSA-163680
Longevity regulating pathwayKEGGhsa04211

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371641542023AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity.1
371641542023AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity.1
364297122022Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings.1
364297122022Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings.1
334447592021Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids.11
337527452021AdipoR2 inhibits human glioblastoma cell growth through the AMPK/mTOR pathway.1
338516852021The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.0
334447592021Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids.11
337527452021AdipoR2 inhibits human glioblastoma cell growth through the AMPK/mTOR pathway.1
338516852021The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.0
327500562020Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.7
327500562020Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.7
301353332019Adiponectin Receptor gene Polymorphisms are Associated with Kidney Function in Elderly Japanese Populations.2
308163112019Adiponectin is associated with cardio-metabolic traits in Mexican children.3
308905622019AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.39

Citation

Dessen P

ADIPOR2 (adiponectin receptor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46466/adipor2-(adiponectin-receptor-2)