Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3214
MIM: 142965
HGNC: 5115
Ensembl: ENSG00000182742
Variants:
dbSNP: 3214
ClinVar: 3214
TCGA: ENSG00000182742
COSMIC: HOXB4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182742 | ENST00000332503 | P17483 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA30128 | KIT | Gene | MultilinkAnnotation | associated | 17253940 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38182548 | 2024 | LINC00629, a HOXB4-downregulated long noncoding RNA, inhibits glycolysis and ovarian cancer progression by destabilizing c-Myc. | 1 |
| 38182548 | 2024 | LINC00629, a HOXB4-downregulated long noncoding RNA, inhibits glycolysis and ovarian cancer progression by destabilizing c-Myc. | 1 |
| 36415199 | 2022 | [miRNA-181a-5p inhibits proliferation and migration of osteosarcoma cell line HOS by targeting HOXB4]. | 0 |
| 36415199 | 2022 | [miRNA-181a-5p inhibits proliferation and migration of osteosarcoma cell line HOS by targeting HOXB4]. | 0 |
| 33479226 | 2021 | HOXB4 inhibits the proliferation and tumorigenesis of cervical cancer cells by downregulating the activity of Wnt/β-catenin signaling pathway. | 12 |
| 33479226 | 2021 | HOXB4 inhibits the proliferation and tumorigenesis of cervical cancer cells by downregulating the activity of Wnt/β-catenin signaling pathway. | 12 |
| 32178630 | 2020 | HOXB4 promotes the malignant progression of ovarian cancer via DHDDS. | 7 |
| 32178630 | 2020 | HOXB4 promotes the malignant progression of ovarian cancer via DHDDS. | 7 |
| 28969513 | 2018 | HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis. | 6 |
| 29660518 | 2018 | HOXB4 knockdown enhances the cytotoxic effect of paclitaxel and cisplatin by downregulating ABC transporters in ovarian cancer cells. | 9 |
| 30419846 | 2018 | MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms. | 7 |
| 28969513 | 2018 | HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis. | 6 |
| 29660518 | 2018 | HOXB4 knockdown enhances the cytotoxic effect of paclitaxel and cisplatin by downregulating ABC transporters in ovarian cancer cells. | 9 |
| 30419846 | 2018 | MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms. | 7 |
| 29039487 | 2017 | Functional analysis of HOXA10 and HOXB4 in human medulloblastoma cell lines. | 6 |
Citation
Dessen P
HOXB4 (homeobox B4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46471/hoxb4-(homeobox-b4)
