Identity
HGNC
LOCATION
2q24.1
LOCUSID
ALIAS
HZF-3,NOT,NURR1,RNR1,TINUR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4929
MIM: 601828
HGNC: 7981
Ensembl: ENSG00000153234
Variants:
dbSNP: 4929
ClinVar: 4929
TCGA: ENSG00000153234
COSMIC: NR4A2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37651006 | 2024 | A role of NR4A2 in Graves' disease: regulation of Th17/Treg. | 2 |
| 38066638 | 2024 | The nuclear receptor Nurr1 is preferentially expressed in human pro-inflammatory macrophages and limits their inflammatory profile. | 0 |
| 38474099 | 2024 | Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia. | 0 |
| 38570607 | 2024 | Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma. | 1 |
| 37651006 | 2024 | A role of NR4A2 in Graves' disease: regulation of Th17/Treg. | 2 |
| 38066638 | 2024 | The nuclear receptor Nurr1 is preferentially expressed in human pro-inflammatory macrophages and limits their inflammatory profile. | 0 |
| 38474099 | 2024 | Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia. | 0 |
| 38570607 | 2024 | Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma. | 1 |
| 36469101 | 2023 | A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors. | 0 |
| 36482877 | 2023 | Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis. | 3 |
| 36577072 | 2023 | The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. | 12 |
| 37569656 | 2023 | Mechanisms of NURR1 Regulation: Consequences for Its Biological Activity and Involvement in Pathology. | 2 |
| 37961948 | 2023 | Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia. | 0 |
| 36469101 | 2023 | A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors. | 0 |
| 36482877 | 2023 | Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis. | 3 |
Citation
Dessen P
NR4A2 (nuclear receptor subfamily 4 group A member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46489
