RNF31 (ring finger protein 31)

2007-02-01  

Identity

HGNC
RNF31
LOCATION
14q12
LOCUSID
55072
ALIAS
HOIP,Paul,ZIBRA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55072
MIM: 612487
HGNC: 16031
Ensembl: ENSG00000092098

Variants:

dbSNP: 55072
ClinVar: 55072
TCGA: ENSG00000092098
COSMIC: RNF31

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092098ENST00000324103Q96EP0
ENSG00000092098ENST00000483895H0YMN0
ENSG00000092098ENST00000491351H0YMG4
ENSG00000092098ENST00000557991H0YM13
ENSG00000092098ENST00000558907H0YMG8
ENSG00000092098ENST00000559260H0YMK6
ENSG00000092098ENST00000559275Q96EP0
ENSG00000092098ENST00000559308H0YM57
ENSG00000092098ENST00000559449H0YNT1
ENSG00000092098ENST00000559533H0YNK5
ENSG00000092098ENST00000559583A0A494C1G4
ENSG00000092098ENST00000559719H0YKI4
ENSG00000092098ENST00000560071H0YNC1
ENSG00000092098ENST00000560787H0YKX0
ENSG00000092098ENST00000560875H0YNJ0

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
Signal TransductionREACTOMER-HSA-162582
Death Receptor SignallingREACTOMER-HSA-73887
TNF signalingREACTOMER-HSA-75893
TNFR1-induced NFkappaB signaling pathwayREACTOMER-HSA-5357956
Regulation of TNFR1 signalingREACTOMER-HSA-5357905

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381721742024RNF31 promotes proliferation and invasion of hepatocellular carcinoma via nuclear factor kappaB activation.0
381721742024RNF31 promotes proliferation and invasion of hepatocellular carcinoma via nuclear factor kappaB activation.0
369977192023RNF31 promotes tumorigenesis via inhibiting RIPK1 kinase-dependent apoptosis.1
373959362023Resonance assignments of the PUB domain of the RNF31 protein.0
369977192023RNF31 promotes tumorigenesis via inhibiting RIPK1 kinase-dependent apoptosis.1
373959362023Resonance assignments of the PUB domain of the RNF31 protein.0
346955702022Effects of removing a highly conserved disulfide bond in ubiquitin-associated domain of human HOIP on biochemical characteristics.0
365819982022RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.6
346955702022Effects of removing a highly conserved disulfide bond in ubiquitin-associated domain of human HOIP on biochemical characteristics.0
365819982022RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.6
344162432021RNF31 mediated ubiquitination of A20 aggravates inflammation and hepatocyte apoptosis through the TLR4/MyD88/NF-κB signaling pathway.1
344162432021RNF31 mediated ubiquitination of A20 aggravates inflammation and hepatocyte apoptosis through the TLR4/MyD88/NF-κB signaling pathway.1
321229702020Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation.4
324032542020Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders.25
332157402020Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.5

Citation

Dessen P

RNF31 (ring finger protein 31)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46497/rnf31-(ring-finger-protein-31)