SERPINH1 (serpin family H member 1)

2007-02-01  

Identity

HGNC
SERPINH1
LOCATION
11q13.5
LOCUSID
871
ALIAS
AsTP3,CBP1,CBP2,HSP47,OI10,PIG14,PPROM,RA-A47,SERPINH2,gp46
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 871
MIM: 600943
HGNC: 1546
Ensembl: ENSG00000149257

Variants:

dbSNP: 871
ClinVar: 871
TCGA: ENSG00000149257
COSMIC: SERPINH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149257ENST00000358171P50454
ENSG00000149257ENST00000358171A0A024R5K8
ENSG00000149257ENST00000524558P50454
ENSG00000149257ENST00000524558A0A024R5K8
ENSG00000149257ENST00000525492E9PQ34
ENSG00000149257ENST00000525611E9PK86
ENSG00000149257ENST00000525876E9PKH2
ENSG00000149257ENST00000526242E9PLA6
ENSG00000149257ENST00000526397E9PMI5
ENSG00000149257ENST00000526638H0YEP8
ENSG00000149257ENST00000528760E9PNX1
ENSG00000149257ENST00000528990E9PIG2
ENSG00000149257ENST00000529643E9PRS3
ENSG00000149257ENST00000530284E9PPV6
ENSG00000149257ENST00000532356E9PR70
ENSG00000149257ENST00000533449E9PJH8
ENSG00000149257ENST00000533603P50454
ENSG00000149257ENST00000533603A0A024R5K8
ENSG00000149257ENST00000649490E9PPV6

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Collagen formationREACTOMER-HSA-1474290
Collagen biosynthesis and modifying enzymesREACTOMER-HSA-1650814

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377121212024Serpin family H member 1 and its related collagen gene network are the potential prognostic biomarkers and anticancer targets for glioma.1
381015772024SERPINH1 variants and thrombotic risk among middle-aged and older adults: a population-based cohort study.0
384324832024Alteration of SERPINH1 is associated with elevated expression in head and neck squamous cell carcinomas and its clinicopathological significance.0
377121212024Serpin family H member 1 and its related collagen gene network are the potential prognostic biomarkers and anticancer targets for glioma.1
381015772024SERPINH1 variants and thrombotic risk among middle-aged and older adults: a population-based cohort study.0
384324832024Alteration of SERPINH1 is associated with elevated expression in head and neck squamous cell carcinomas and its clinicopathological significance.0
363159872023High Levels of Heat Shock Protein 47 in the Aqueous Humor of Patients with Acute Primary Angle Closure.0
363716722023Biglycan promotes hepatic fibrosis through activating heat shock protein 47.3
379519792023HSP47 levels determine the degree of body adiposity.0
380553822023miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway.0
363159872023High Levels of Heat Shock Protein 47 in the Aqueous Humor of Patients with Acute Primary Angle Closure.0
363716722023Biglycan promotes hepatic fibrosis through activating heat shock protein 47.3
379519792023HSP47 levels determine the degree of body adiposity.0
380553822023miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway.0
349989322022Regulation of the unfolded protein response transducer IRE1α by SERPINH1 aggravates periodontitis with diabetes mellitus via prolonged ER stress.4

Citation

Dessen P

SERPINH1 (serpin family H member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46500