Identity
HGNC
LOCATION
11q13.5
LOCUSID
ALIAS
AsTP3,CBP1,CBP2,HSP47,OI10,PIG14,PPROM,RA-A47,SERPINH2,gp46
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 871
MIM: 600943
HGNC: 1546
Ensembl: ENSG00000149257
Variants:
dbSNP: 871
ClinVar: 871
TCGA: ENSG00000149257
COSMIC: SERPINH1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| Collagen formation | REACTOME | R-HSA-1474290 |
| Collagen biosynthesis and modifying enzymes | REACTOME | R-HSA-1650814 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37712121 | 2024 | Serpin family H member 1 and its related collagen gene network are the potential prognostic biomarkers and anticancer targets for glioma. | 1 |
| 38101577 | 2024 | SERPINH1 variants and thrombotic risk among middle-aged and older adults: a population-based cohort study. | 0 |
| 38432483 | 2024 | Alteration of SERPINH1 is associated with elevated expression in head and neck squamous cell carcinomas and its clinicopathological significance. | 0 |
| 37712121 | 2024 | Serpin family H member 1 and its related collagen gene network are the potential prognostic biomarkers and anticancer targets for glioma. | 1 |
| 38101577 | 2024 | SERPINH1 variants and thrombotic risk among middle-aged and older adults: a population-based cohort study. | 0 |
| 38432483 | 2024 | Alteration of SERPINH1 is associated with elevated expression in head and neck squamous cell carcinomas and its clinicopathological significance. | 0 |
| 36315987 | 2023 | High Levels of Heat Shock Protein 47 in the Aqueous Humor of Patients with Acute Primary Angle Closure. | 0 |
| 36371672 | 2023 | Biglycan promotes hepatic fibrosis through activating heat shock protein 47. | 3 |
| 37951979 | 2023 | HSP47 levels determine the degree of body adiposity. | 0 |
| 38055382 | 2023 | miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway. | 0 |
| 36315987 | 2023 | High Levels of Heat Shock Protein 47 in the Aqueous Humor of Patients with Acute Primary Angle Closure. | 0 |
| 36371672 | 2023 | Biglycan promotes hepatic fibrosis through activating heat shock protein 47. | 3 |
| 37951979 | 2023 | HSP47 levels determine the degree of body adiposity. | 0 |
| 38055382 | 2023 | miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway. | 0 |
| 34998932 | 2022 | Regulation of the unfolded protein response transducer IRE1α by SERPINH1 aggravates periodontitis with diabetes mellitus via prolonged ER stress. | 4 |
Citation
Dessen P
SERPINH1 (serpin family H member 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46500
