IL17RB (interleukin 17 receptor B)

2007-02-01  

Identity

HGNC
LOCATION
3p21.1
LOCUSID
ALIAS
CRL4,EVI27,IL17BR,IL17RH1

Other Information

Locus ID:

NCBI: 55540
MIM: 605458
HGNC: 18015
Ensembl: ENSG00000056736

Variants:

dbSNP: 55540
ClinVar: 55540
TCGA: ENSG00000056736
COSMIC: IL17RB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000056736ENST00000288167Q9NRM6
ENSG00000056736ENST00000494338C9IZN0

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-17 signalingREACTOMER-HSA-448424
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
170087032006The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer.60
215707192011Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses.53
166090192006A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen.37
269909862016Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon.37
257323062015Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines.35
179751442007The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer.30
238515032014Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-κB-mediated antiapoptotic pathway.30
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.23

Citation

Dessen P

IL17RB (interleukin 17 receptor B)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46582/il17rb-(interleukin-17-receptor-b)