Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
E2-F1,L-UBC,UBCH7,UbcM4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7332
MIM: 603721
HGNC: 12488
Ensembl: ENSG00000185651
Variants:
dbSNP: 7332
ClinVar: 7332
TCGA: ENSG00000185651
COSMIC: UBE2L3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185651 | ENST00000342192 | P68036 |
| ENSG00000185651 | ENST00000342192 | A0A024R1A4 |
| ENSG00000185651 | ENST00000458578 | P68036 |
| ENSG00000185651 | ENST00000545681 | P68036 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38226814 | 2024 | The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer. | 2 |
| 38301893 | 2024 | The E3 ligase SMURF1 stabilizes p27 via UbcH7 catalyzed K29-linked ubiquitin chains to promote cell migration SMURF1-UbcH7 K29 ubiquitination of p27 and cell migration. | 1 |
| 38656363 | 2024 | UBE2L3 expression in human gastric cancer and its clinical significance. | 0 |
| 38795139 | 2024 | Role of Ubiquitin-conjugating enzyme E2 (UBE2) in two immune-mediated inflammatory skin diseases: a mendelian randomization analysis. | 0 |
| 38226814 | 2024 | The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer. | 2 |
| 38301893 | 2024 | The E3 ligase SMURF1 stabilizes p27 via UbcH7 catalyzed K29-linked ubiquitin chains to promote cell migration SMURF1-UbcH7 K29 ubiquitination of p27 and cell migration. | 1 |
| 38656363 | 2024 | UBE2L3 expression in human gastric cancer and its clinical significance. | 0 |
| 38795139 | 2024 | Role of Ubiquitin-conjugating enzyme E2 (UBE2) in two immune-mediated inflammatory skin diseases: a mendelian randomization analysis. | 0 |
| 36502938 | 2023 | UBE2L3 Reduces TRIM21 Expression and IL-1β Secretion in Epidermal Keratinocytes and Improves Psoriasis-Like Skin. | 3 |
| 37001433 | 2023 | UBE2L3 regulates TLR7-induced B cell autoreactivity in Systemic Lupus Erythematosus. | 7 |
| 36502938 | 2023 | UBE2L3 Reduces TRIM21 Expression and IL-1β Secretion in Epidermal Keratinocytes and Improves Psoriasis-Like Skin. | 3 |
| 37001433 | 2023 | UBE2L3 regulates TLR7-induced B cell autoreactivity in Systemic Lupus Erythematosus. | 7 |
| 34279042 | 2022 | Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. | 3 |
| 35128752 | 2022 | UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation. | 4 |
| 34279042 | 2022 | Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. | 3 |
Citation
Dessen P
UBE2L3 (ubiquitin conjugating enzyme E2 L3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46591/ube2l3-(ubiquitin-conjugating-enzyme-e2-l3)
