Identity
HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
IEGF,MSTP036,SCDGF-B,SCDGFB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80310
MIM: 609673
HGNC: 30620
Ensembl: ENSG00000170962
Variants:
dbSNP: 80310
ClinVar: 80310
TCGA: ENSG00000170962
COSMIC: PDGFD
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170962 | ENST00000302251 | Q9GZP0 |
| ENSG00000170962 | ENST00000393158 | Q9GZP0 |
| ENSG00000170962 | ENST00000529268 | H0YD37 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38705811 | 2024 | The role of THBS1 and PDGFD in the immune microenvironment of Helicobacter pylori-associated gastric cancer. | 0 |
| 38705811 | 2024 | The role of THBS1 and PDGFD in the immune microenvironment of Helicobacter pylori-associated gastric cancer. | 0 |
| 35568735 | 2023 | Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression. | 0 |
| 36413571 | 2023 | Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-β reveals anticancer effect in breast cancer. | 1 |
| 37253627 | 2023 | lncRNA PITPNA-AS1 promotes cell proliferation and metastasis in hepatocellular carcinoma by upregulating PDGFD. | 1 |
| 37321532 | 2023 | Reversible promoter demethylation of PDGFD confers gemcitabine resistance through STAT3 activation and RRM1 upregulation. | 2 |
| 35568735 | 2023 | Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression. | 0 |
| 36413571 | 2023 | Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-β reveals anticancer effect in breast cancer. | 1 |
| 37253627 | 2023 | lncRNA PITPNA-AS1 promotes cell proliferation and metastasis in hepatocellular carcinoma by upregulating PDGFD. | 1 |
| 37321532 | 2023 | Reversible promoter demethylation of PDGFD confers gemcitabine resistance through STAT3 activation and RRM1 upregulation. | 2 |
| 35027451 | 2022 | PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival. | 13 |
| 35472332 | 2022 | E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR. | 2 |
| 36308081 | 2022 | ZNF561 antisense RNA 1 contributes to angiogenesis in hepatocellular carcinoma through upregulation of platelet-derived growth Factor-D. | 0 |
| 35027451 | 2022 | PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival. | 13 |
| 35472332 | 2022 | E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR. | 2 |
Citation
Dessen P
PDGFD (platelet derived growth factor D)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46596/pdgfd-(platelet-derived-growth-factor-d)
