Identity
HGNC
LOCATION
12q22
LOCUSID
ALIAS
MST105,MSTP105,ZFYVE2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8411
MIM: 605070
HGNC: 3185
Ensembl: ENSG00000102189
Variants:
dbSNP: 8411
ClinVar: 8411
TCGA: ENSG00000102189
COSMIC: EEA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102189 | ENST00000322349 | Q15075 |
| ENSG00000102189 | ENST00000418984 | F8WE79 |
| ENSG00000102189 | ENST00000549790 | F8W119 |
| ENSG00000102189 | ENST00000553019 | F8VUZ7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32357161 | 2020 | Functional cycle of EEA1-positive early endosome: Direct evidence for pre-existing compartment of degradative pathway. | 15 |
| 32357161 | 2020 | Functional cycle of EEA1-positive early endosome: Direct evidence for pre-existing compartment of degradative pathway. | 15 |
| 29437530 | 2018 | Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation. | 18 |
| 29547649 | 2018 | Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages. | 9 |
| 29437530 | 2018 | Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation. | 18 |
| 29547649 | 2018 | Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages. | 9 |
| 26993163 | 2016 | Mobility of tethering factor EEA1 on endosomes is decreased upon stimulation of EGF receptor endocytosis in HeLa cells. | 1 |
| 27556945 | 2016 | An endosomal tether undergoes an entropic collapse to bring vesicles together. | 60 |
| 30188634 | 2016 | EEA1 CARRYING VESICLES ARE NOT AUTOPHAGOSOMES IN SERUM-DEPRIVED HeLa CELLS. | 1 |
| 26993163 | 2016 | Mobility of tethering factor EEA1 on endosomes is decreased upon stimulation of EGF receptor endocytosis in HeLa cells. | 1 |
| 27556945 | 2016 | An endosomal tether undergoes an entropic collapse to bring vesicles together. | 60 |
| 30188634 | 2016 | EEA1 CARRYING VESICLES ARE NOT AUTOPHAGOSOMES IN SERUM-DEPRIVED HeLa CELLS. | 1 |
| 25998683 | 2015 | Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes. | 31 |
| 25998683 | 2015 | Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes. | 31 |
| 24491918 | 2014 | HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling. | 11 |
Citation
Dessen P
EEA1 (early endosome antigen 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46636/eea1-(early-endosome-antigen-1)
