Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5300
MIM: 601052
HGNC: 8988
Ensembl: ENSG00000127445
Variants:
dbSNP: 5300
ClinVar: 5300
TCGA: ENSG00000127445
COSMIC: PIN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA131285527 | oxaliplatin | Chemical | ClinicalAnnotation | associated | PD | ||
| PA166123026 | progression-free survival | Disease | VariantAnnotation | associated | PD | ||
| PA446108 | Colorectal Neoplasms | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA450085 | irinotecan | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37929660 | 2024 | PIN1P1 is activated by CREB1 and promotes gastric cancer progression via interacting with YBX1 and upregulating PIN1. | 2 |
| 38084839 | 2024 | Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling. | 1 |
| 38147203 | 2024 | The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m(6)A-dependent stabilization of AURKA mRNA. | 0 |
| 38167292 | 2024 | Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells. | 0 |
| 38216124 | 2024 | Nuclear Phosphoproteome Reveals Prolyl Isomerase PIN1 as a Modulator of Oncogene-Induced Senescence. | 0 |
| 38619104 | 2024 | Stereospecific NANOG PEST Stabilization by Pin1. | 0 |
| 37929660 | 2024 | PIN1P1 is activated by CREB1 and promotes gastric cancer progression via interacting with YBX1 and upregulating PIN1. | 2 |
| 38084839 | 2024 | Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling. | 1 |
| 38147203 | 2024 | The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m(6)A-dependent stabilization of AURKA mRNA. | 0 |
| 38167292 | 2024 | Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells. | 0 |
| 38216124 | 2024 | Nuclear Phosphoproteome Reveals Prolyl Isomerase PIN1 as a Modulator of Oncogene-Induced Senescence. | 0 |
| 38619104 | 2024 | Stereospecific NANOG PEST Stabilization by Pin1. | 0 |
| 36162703 | 2023 | Pin1 and Alzheimer's disease. | 4 |
| 36755057 | 2023 | METTL3 stabilization by PIN1 promotes breast tumorigenesis via enhanced m(6)A-dependent translation. | 5 |
| 36766769 | 2023 | Spastin Promotes the Migration and Invasion Capability of T98G Glioblastoma Cells by Interacting with Pin1 through Its Microtubule-Binding Domain. | 0 |
Citation
Dessen P
PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/467/pin1
