Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7182
MIM: 601426
HGNC: 7972
Ensembl: ENSG00000177463
Variants:
dbSNP: 7182
ClinVar: 7182
TCGA: ENSG00000177463
COSMIC: NR2C2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
| Nuclear Receptor transcription pathway | REACTOME | R-HSA-383280 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38429762 | 2024 | TR4 worsen urosepsis by regulating GSDMD. | 0 |
| 38569496 | 2024 | Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia. | 1 |
| 38429762 | 2024 | TR4 worsen urosepsis by regulating GSDMD. | 0 |
| 38569496 | 2024 | Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia. | 1 |
| 36651297 | 2023 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. | 1 |
| 36651297 | 2023 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. | 1 |
| 35184673 | 2022 | Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment. | 0 |
| 35513391 | 2022 | Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1. | 13 |
| 36270986 | 2022 | HDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer. | 4 |
| 35184673 | 2022 | Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment. | 0 |
| 35513391 | 2022 | Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1. | 13 |
| 36270986 | 2022 | HDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer. | 4 |
| 33650661 | 2021 | Use of miR‑145 and testicular nuclear receptor 4 inhibition to reduce chemoresistance to docetaxel in prostate cancer. | 2 |
| 34075691 | 2021 | The stabilization of yes-associated protein by TGFβ-activated kinase 1 regulates the self-renewal and oncogenesis of gastric cancer stem cells. | 4 |
| 34830460 | 2021 | Takinib Inhibits Inflammation in Human Rheumatoid Arthritis Synovial Fibroblasts by Targeting the Janus Kinase-Signal Transducer and Activator of Transcription 3 (JAK/STAT3) Pathway. | 6 |
Citation
Dessen P
NR2C2 (nuclear receptor subfamily 2 group C member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46702/nr2c2-(nuclear-receptor-subfamily-2-group-c-member-2)
