PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase like 1)

2007-04-01  

Identity

HGNC
PIP5KL1
LOCATION
9q34.11
LOCUSID
138429
ALIAS
PIPKH
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 138429
MIM: 612865
HGNC: 28711
Ensembl: ENSG00000167103

Variants:

dbSNP: 138429
ClinVar: 138429
TCGA: ENSG00000167103
COSMIC: PIP5KL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167103ENST00000300432Q5T9C9
ENSG00000167103ENST00000388747Q5T9C9

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Inositol phosphate metabolismKEGGko00562
Inositol phosphate metabolismKEGGhsa00562
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Metabolic pathwaysKEGGhsa01100
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4KEGGhsa_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4KEGGM00130

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
316160092019Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P(2) distribution and the localization of small G-proteins.3
316160092019Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P(2) distribution and the localization of small G-proteins.3
196807872010Overexpression of PIP5KL1 suppresses cell proliferation and migration in human gastric cancer cells.6
196807872010Overexpression of PIP5KL1 suppresses cell proliferation and migration in human gastric cancer cells.6
147018392004Identification and characterization of a phosphoinositide phosphate kinase homolog.11
147018392004Identification and characterization of a phosphoinositide phosphate kinase homolog.11

Citation

Dessen P

PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46713/pip5kl1-(phosphatidylinositol-4-phosphate-5-kinase-like-1)