Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 65057
MIM: 609377
HGNC: 25070
Ensembl: ENSG00000102977
Variants:
dbSNP: 65057
ClinVar: 65057
TCGA: ENSG00000102977
COSMIC: ACD
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38176734 | 2024 | Characterization of novel mutations in the TEL-patch domain of the telomeric factor TPP1 associated with telomere biology disorders. | 0 |
| 38722833 | 2024 | TPP1 is associated with risk of advanced precursors and cervical cancer survival. | 0 |
| 38176734 | 2024 | Characterization of novel mutations in the TEL-patch domain of the telomeric factor TPP1 associated with telomere biology disorders. | 0 |
| 38722833 | 2024 | TPP1 is associated with risk of advanced precursors and cervical cancer survival. | 0 |
| 36649908 | 2023 | Complex interaction network revealed by mutation of human telomerase 'insertion in fingers' and essential N-terminal domains and the telomere protein TPP1. | 1 |
| 37021555 | 2023 | CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension. | 5 |
| 36649908 | 2023 | Complex interaction network revealed by mutation of human telomerase 'insertion in fingers' and essential N-terminal domains and the telomere protein TPP1. | 1 |
| 37021555 | 2023 | CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension. | 5 |
| 35201900 | 2022 | Structural basis of human telomerase recruitment by TPP1-POT1. | 34 |
| 35418675 | 2022 | Structure of active human telomerase with telomere shelterin protein TPP1. | 38 |
| 36356143 | 2022 | TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma. | 6 |
| 35201900 | 2022 | Structural basis of human telomerase recruitment by TPP1-POT1. | 34 |
| 35418675 | 2022 | Structure of active human telomerase with telomere shelterin protein TPP1. | 38 |
| 36356143 | 2022 | TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma. | 6 |
| 33446513 | 2021 | Identification and characterization of novel ACD variants: modulation of TPP1 protein level offsets the impact of germline loss-of-function variants on telomere length. | 3 |
Citation
Dessen P
ACD (ACD shelterin complex subunit and telomerase recruitment factor)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46714
