Identity
HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
ADAM-TS10,ADAMTS-10,WMS,WMS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81794
MIM: 608990
HGNC: 13201
Ensembl: ENSG00000142303
Variants:
dbSNP: 81794
ClinVar: 81794
TCGA: ENSG00000142303
COSMIC: ADAMTS10
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37240210 | 2023 | A Novel Mutation in the ADAMTS10 Associated with Weil-Marchesani Syndrome with a Unique Presentation of Developed Membranes Causing Severe Stenosis of the Supra Pulmonic, Supramitral, and Subaortic Areas in the Heart. | 0 |
| 37240210 | 2023 | A Novel Mutation in the ADAMTS10 Associated with Weil-Marchesani Syndrome with a Unique Presentation of Developed Membranes Causing Severe Stenosis of the Supra Pulmonic, Supramitral, and Subaortic Areas in the Heart. | 0 |
| 35925524 | 2022 | ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer. | 7 |
| 35925524 | 2022 | ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer. | 7 |
| 27779234 | 2016 | ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. | 39 |
| 27779234 | 2016 | ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. | 39 |
| 23422823 | 2013 | Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles. | 16 |
| 23422823 | 2013 | Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles. | 16 |
| 21402694 | 2011 | ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts. | 74 |
| 21402694 | 2011 | ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts. | 74 |
| 19696795 | 2009 | Clinical and genetic investigation of isolated microspherophakia in a consanguineous Tunisian family. | 10 |
| 19836009 | 2009 | Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. | 109 |
| 19696795 | 2009 | Clinical and genetic investigation of isolated microspherophakia in a consanguineous Tunisian family. | 10 |
| 19836009 | 2009 | Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. | 109 |
| 18567016 | 2008 | Functional analysis of an ADAMTS10 signal peptide mutation in Weill-Marchesani syndrome demonstrates a long-range effect on secretion of the full-length enzyme. | 28 |
Citation
Dessen P
ADAMTS10 (ADAM metallopeptidase with thrombospondin type 1 motif 10)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46725/adamts10-(adam-metallopeptidase-with-thrombospondin-type-1-motif-10)
