Identity
HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
CLN4,CLN4B,CSP,DNAJC5A,NCL,mir-941-2,mir-941-3,mir-941-4,mir-941-5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80331
MIM: 611203
HGNC: 16235
Ensembl: ENSG00000101152
Variants:
dbSNP: 80331
ClinVar: 80331
TCGA: ENSG00000101152
COSMIC: DNAJC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101152 | ENST00000360864 | Q9H3Z4 |
| ENSG00000101152 | ENST00000470551 | Q9H3Z4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38348704 | 2024 | LINC00624 affects hepatocellular carcinoma proliferation and apoptosis through the miR-342-3p/DNAJC5 axis. | 0 |
| 38348704 | 2024 | LINC00624 affects hepatocellular carcinoma proliferation and apoptosis through the miR-342-3p/DNAJC5 axis. | 0 |
| 35506243 | 2023 | Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation. | 14 |
| 36308432 | 2023 | The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble in trans-complexes during human sperm acrosomal exocytosis†. | 1 |
| 36626307 | 2023 | Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers. | 4 |
| 35506243 | 2023 | Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation. | 14 |
| 36308432 | 2023 | The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble in trans-complexes during human sperm acrosomal exocytosis†. | 1 |
| 36626307 | 2023 | Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers. | 4 |
| 32783189 | 2021 | Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis. | 14 |
| 33662413 | 2021 | DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation. | 5 |
| 32783189 | 2021 | Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis. | 14 |
| 33662413 | 2021 | DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation. | 5 |
| 31919451 | 2020 | Autosomal-dominant adult neuronal ceroid lipofuscinosis caused by duplication in DNAJC5 initially missed by Sanger and whole-exome sequencing. | 9 |
| 32042150 | 2020 | Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators. | 12 |
| 31919451 | 2020 | Autosomal-dominant adult neuronal ceroid lipofuscinosis caused by duplication in DNAJC5 initially missed by Sanger and whole-exome sequencing. | 9 |
Citation
Dessen P
DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46733/dnajc5-(dnaj-heat-shock-protein-family-(hsp40)-member-c5)
