SLC4A10 (solute carrier family 4 member 10)

2007-04-01  

Identity

HGNC
SLC4A10
LOCATION
2q24.2
LOCUSID
57282
ALIAS
NBCn2,NCBE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57282
MIM: 605556
HGNC: 13811
Ensembl: ENSG00000144290

Variants:

dbSNP: 57282
ClinVar: 57282
TCGA: ENSG00000144290
COSMIC: SLC4A10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144290ENST00000272716C9J240
ENSG00000144290ENST00000375514Q6U841
ENSG00000144290ENST00000415876Q6U841
ENSG00000144290ENST00000421911E7EW28
ENSG00000144290ENST00000446228F8WDX9
ENSG00000144290ENST00000446997Q6U841

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Bicarbonate transportersREACTOMER-HSA-425381

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
183192542008Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity.48
184134822008Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation.30
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.29
201012822010AQP1 and SLC4A10 as candidate genes for primary open-angle glaucoma.5
201012822010AQP1 and SLC4A10 as candidate genes for primary open-angle glaucoma.5
283602212017NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.5

Citation

Dessen P

SLC4A10 (solute carrier family 4 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46744/slc4a10-(solute-carrier-family-4-member-10)