ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14)

2007-04-01  

Identity

HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 140766
MIM: 607506
HGNC: 14899
Ensembl: ENSG00000138316

Variants:

dbSNP: 140766
ClinVar: 140766
TCGA: ENSG00000138316
COSMIC: ADAMTS14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138316ENST00000373207Q8WXS8
ENSG00000138316ENST00000373208Q8WXS8

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-glycosylation of TSR domain-containing proteinsREACTOMER-HSA-5173214
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Extracellular matrix organizationREACTOMER-HSA-1474244
Collagen formationREACTOMER-HSA-1474290
Collagen biosynthesis and modifying enzymesREACTOMER-HSA-1650814
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective B3GALTL causes Peters-plus syndrome (PpS)REACTOMER-HSA-5083635

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
258631612015The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.25
187906542009Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes.22
274639662016ADAMTS14 Gene Polymorphism and Environmental Risk in the Development of Oral Cancer.17
234911412013Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study.16
256381642015Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.11
243017912013ADAMTS14 gene polymorphism associated with knee osteoarthritis in Thai women.10
303175402019The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1.8
159137952005Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis.7

Citation

Dessen P

ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46785/adamts14-(adam-metallopeptidase-with-thrombospondin-type-1-motif-14)