Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
PI5P4KB,PIP5K2B,PIP5KIIB,PIP5KIIbeta,PIP5P4KB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8396
MIM: 603261
HGNC: 8998
Ensembl: ENSG00000276293
Variants:
dbSNP: 8396
ClinVar: 8396
TCGA: ENSG00000276293
COSMIC: PIP4K2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000276293 | ENST00000617499 | A0A087WT35 |
| ENSG00000276293 | ENST00000619039 | P78356 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36856076 | 2023 | Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ. | 1 |
| 36918565 | 2023 | PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1. | 6 |
| 36982700 | 2023 | Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis. | 3 |
| 36856076 | 2023 | Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ. | 1 |
| 36918565 | 2023 | PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1. | 6 |
| 36982700 | 2023 | Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis. | 3 |
| 34001596 | 2021 | Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells. | 17 |
| 34001596 | 2021 | Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells. | 17 |
| 31091439 | 2019 | PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism. | 27 |
| 31488171 | 2019 | Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression. | 36 |
| 31091439 | 2019 | PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism. | 27 |
| 31488171 | 2019 | Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression. | 36 |
| 27132569 | 2016 | PIP4K2B: Coupling GTP Sensing to PtdIns5P Levels to Regulate Tumorigenesis. | 2 |
| 27132569 | 2016 | PIP4K2B: Coupling GTP Sensing to PtdIns5P Levels to Regulate Tumorigenesis. | 2 |
| 25728392 | 2015 | PIP4K and the role of nuclear phosphoinositides in tumour suppression. | 34 |
Citation
Dessen P
PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase type 2 beta)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46799/pip4k2b-(phosphatidylinositol-5-phosphate-4-kinase-type-2-beta)
