FOXC2 (forkhead box C2)

2007-04-01  

Identity

HGNC
LOCATION
16q24.1
LOCUSID
ALIAS
FKHL14,LD,MFH-1,MFH1

Other Information

Locus ID:

NCBI: 2303
MIM: 602402
HGNC: 3801
Ensembl: ENSG00000176692

Variants:

dbSNP: 2303
ClinVar: 2303
TCGA: ENSG00000176692
COSMIC: FOXC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176692ENST00000649859Q99958

Expression (GTEx)

0
10
20
30
40
50
60
70
80

References

Pubmed IDYearTitleCitations
385800852024Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects.0
386081232024The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer.0
385800852024Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects.0
386081232024The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer.0
367409862023The FOXC2 Transcription Factor: A Master Regulator of Chemoresistance in Cancer.0
368055382023Up-regulation of microRNA-183 reduces FOXO1 expression in gastric cancer patients with Helicobacter pylori infection.2
370728872023Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.0
377057412023FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts.1
367409862023The FOXC2 Transcription Factor: A Master Regulator of Chemoresistance in Cancer.0
368055382023Up-regulation of microRNA-183 reduces FOXO1 expression in gastric cancer patients with Helicobacter pylori infection.2
370728872023Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.0
377057412023FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts.1
346565272022Digenic Inheritance of a FOXC2 Mutation and Two PIEZO1 Mutations Underlies Congenital Lymphedema in a Multigeneration Family.1
355322012022Forkhead box C2 is associated with insulin resistance in gestational diabetes mellitus.0
357167612022Genetic landscape of FOXC2 mutations in lymphedema-distichiasis syndrome: Different mechanism of pathogenicity for mutations in different domains.1

Citation

Dessen P

FOXC2 (forkhead box C2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46819/foxc2-(forkhead-box-c2)